Refining the adriamycin‐induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare
Abstract Background Reliable animal models are crucial to drug development for focal segmental glomerulosclerosis (FSGS), a rare kidney disease. Variability in success rates in literature and significant ethical concerns with animal welfare necessitate further optimization of adriamycin (ADR)–induce...
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| Main Authors: | Haochen Jiang, Salma Althobaiti, Braeden Pinkerton, Xin Fu, Zhenshan Jia, Kirk W. Foster, Geoffrey M. Thiele, Troy J. Plumb, Dong Wang |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-05-01
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| Series: | Animal Models and Experimental Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ame2.12564 |
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