NEUROPEPTIDE S100-b: THE DIAGNOSIS OF A MALIGNANT CEREBROVASCULAR ACCIDENT

The major heart attack in the carotid system, going with the cerebral edema is considered to date as the most mortal type of the ischemic stroke. The only prove successful treatment policy is the decompressive craniectomy. The early start of the operative intervention, reported in the references, br...

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Main Authors: T. Yu. Shaytanova, V. A. Saskin, E. V. Nedashkovsky
Format: Article
Language:Russian
Published: New Terra Publishing House 2017-11-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/31
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author T. Yu. Shaytanova
V. A. Saskin
E. V. Nedashkovsky
author_facet T. Yu. Shaytanova
V. A. Saskin
E. V. Nedashkovsky
author_sort T. Yu. Shaytanova
collection DOAJ
description The major heart attack in the carotid system, going with the cerebral edema is considered to date as the most mortal type of the ischemic stroke. The only prove successful treatment policy is the decompressive craniectomy. The early start of the operative intervention, reported in the references, brings about improvement of the clinical outcomes, however under limited time the diagnostics issues remain open and, as a consequence there perform the unreasonable traumatic operational assistance. 43 patients with the severe ischemic stroke were examined and an analysis of the S100-b glial peptide as a marker of malignant brain infarction course was performed. The neuropeptide monitoring in the blood serum allows detection of the responders to the decompressive craniectomy among the high-risk patients within 12-16 hours of the disease onset till the clinical deterioration development, when according to the computerized tomography the certain changes have not in yet.
format Article
id doaj-art-6492fd4c65b848ee9fda0ec627a81230
institution DOAJ
issn 2078-5658
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language Russian
publishDate 2017-11-01
publisher New Terra Publishing House
record_format Article
series Вестник анестезиологии и реаниматологии
spelling doaj-art-6492fd4c65b848ee9fda0ec627a812302025-08-20T02:59:46ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532017-11-01123485510.21292/2078-5658-2015-12-3-48-5531NEUROPEPTIDE S100-b: THE DIAGNOSIS OF A MALIGNANT CEREBROVASCULAR ACCIDENTT. Yu. Shaytanova0V. A. Saskin1E. V. Nedashkovsky2E. E. Volosevich First Municipal Clinical Hospital, ArkhangelskE. E. Volosevich First Municipal Clinical Hospital, ArkhangelskNorthern State Medical University, ArkhangelskThe major heart attack in the carotid system, going with the cerebral edema is considered to date as the most mortal type of the ischemic stroke. The only prove successful treatment policy is the decompressive craniectomy. The early start of the operative intervention, reported in the references, brings about improvement of the clinical outcomes, however under limited time the diagnostics issues remain open and, as a consequence there perform the unreasonable traumatic operational assistance. 43 patients with the severe ischemic stroke were examined and an analysis of the S100-b glial peptide as a marker of malignant brain infarction course was performed. The neuropeptide monitoring in the blood serum allows detection of the responders to the decompressive craniectomy among the high-risk patients within 12-16 hours of the disease onset till the clinical deterioration development, when according to the computerized tomography the certain changes have not in yet.https://www.vair-journal.com/jour/article/view/31s100-bbiomarkersischemic strokemalignant cerebral edemadecompressive craniectomy
spellingShingle T. Yu. Shaytanova
V. A. Saskin
E. V. Nedashkovsky
NEUROPEPTIDE S100-b: THE DIAGNOSIS OF A MALIGNANT CEREBROVASCULAR ACCIDENT
Вестник анестезиологии и реаниматологии
s100-b
biomarkers
ischemic stroke
malignant cerebral edema
decompressive craniectomy
title NEUROPEPTIDE S100-b: THE DIAGNOSIS OF A MALIGNANT CEREBROVASCULAR ACCIDENT
title_full NEUROPEPTIDE S100-b: THE DIAGNOSIS OF A MALIGNANT CEREBROVASCULAR ACCIDENT
title_fullStr NEUROPEPTIDE S100-b: THE DIAGNOSIS OF A MALIGNANT CEREBROVASCULAR ACCIDENT
title_full_unstemmed NEUROPEPTIDE S100-b: THE DIAGNOSIS OF A MALIGNANT CEREBROVASCULAR ACCIDENT
title_short NEUROPEPTIDE S100-b: THE DIAGNOSIS OF A MALIGNANT CEREBROVASCULAR ACCIDENT
title_sort neuropeptide s100 b the diagnosis of a malignant cerebrovascular accident
topic s100-b
biomarkers
ischemic stroke
malignant cerebral edema
decompressive craniectomy
url https://www.vair-journal.com/jour/article/view/31
work_keys_str_mv AT tyushaytanova neuropeptides100bthediagnosisofamalignantcerebrovascularaccident
AT vasaskin neuropeptides100bthediagnosisofamalignantcerebrovascularaccident
AT evnedashkovsky neuropeptides100bthediagnosisofamalignantcerebrovascularaccident