Near-Infrared Confocal Reflectance Scanning Laser Ophthalmoscopy (SLO) and Short-Wavelength Autofluorescence Imaging in Cystic Diabetic Macular Edema
Objective. To characterize results of short-wavelength autofluorescent (SW-AF) and near-infrared confocal reflectance scanning laser ophthalmoscopy (NIR-cR SLO) imaging in cystic diabetic macular edema (DME). Design. Cross-sectional study. Participants: 104 eyes from 52 naïve treatment patients with...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2022/6831396 |
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| author | Fariba Ghassemi Fatemeh Bazvand Houshang Faghihi Ramak Roohipourmoallai Maryam Masoumi Sepide Jamali Masoumeh Mohebbi Siamak Sabour |
| author_facet | Fariba Ghassemi Fatemeh Bazvand Houshang Faghihi Ramak Roohipourmoallai Maryam Masoumi Sepide Jamali Masoumeh Mohebbi Siamak Sabour |
| author_sort | Fariba Ghassemi |
| collection | DOAJ |
| description | Objective. To characterize results of short-wavelength autofluorescent (SW-AF) and near-infrared confocal reflectance scanning laser ophthalmoscopy (NIR-cR SLO) imaging in cystic diabetic macular edema (DME). Design. Cross-sectional study. Participants: 104 eyes from 52 naïve treatment patients with DME and mild to moderate nonproliferative diabetic retinopathy (NPDR) Methods: complete ocular examination, best-corrected visual acuity (BCVA), and imaging were performed. Results. In NIR-cR SLO, small/medium and large-sized cysts presented with decreased and increased reflectance, respectively. In SW-AF, increased and decreased autofluorescence, corresponding to medium-/large- and small-sized cysts were noted. Mainly, the lower NIR reflectance was associated with petaloid edema pattern in SW-AF (P=0.011), BCVA (logMAR) (P=0.056), subretinal fluid (P=0.035), and the involved layers of retina by cysts (P<0.001) in Pearson chi-square test. Fair agreement of 0.31 (P<0.001) between NIR-cR SLO and late FA leakage was found by the weighted kappa test. In regression analysis, NIR-cR SLO abnormality is highly correlated with outer and inner nuclear layers location of the cystic changes. Conclusions. The size of cysts and involved layers affect presenting features of SW-AF and NIR reflectance. |
| format | Article |
| id | doaj-art-6482b8b6220d448f87f0f42034701c0a |
| institution | Kabale University |
| issn | 2090-0058 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-6482b8b6220d448f87f0f42034701c0a2025-08-20T03:34:25ZengWileyJournal of Ophthalmology2090-00582022-01-01202210.1155/2022/6831396Near-Infrared Confocal Reflectance Scanning Laser Ophthalmoscopy (SLO) and Short-Wavelength Autofluorescence Imaging in Cystic Diabetic Macular EdemaFariba Ghassemi0Fatemeh Bazvand1Houshang Faghihi2Ramak Roohipourmoallai3Maryam Masoumi4Sepide Jamali5Masoumeh Mohebbi6Siamak Sabour7Eye Research CenterEye Research CenterEye Research CenterDepartmant of OphthalmologyEye Research CenterEye Research CenterEye Research CenterSafety Promotion and Injury Prevention Research CenterObjective. To characterize results of short-wavelength autofluorescent (SW-AF) and near-infrared confocal reflectance scanning laser ophthalmoscopy (NIR-cR SLO) imaging in cystic diabetic macular edema (DME). Design. Cross-sectional study. Participants: 104 eyes from 52 naïve treatment patients with DME and mild to moderate nonproliferative diabetic retinopathy (NPDR) Methods: complete ocular examination, best-corrected visual acuity (BCVA), and imaging were performed. Results. In NIR-cR SLO, small/medium and large-sized cysts presented with decreased and increased reflectance, respectively. In SW-AF, increased and decreased autofluorescence, corresponding to medium-/large- and small-sized cysts were noted. Mainly, the lower NIR reflectance was associated with petaloid edema pattern in SW-AF (P=0.011), BCVA (logMAR) (P=0.056), subretinal fluid (P=0.035), and the involved layers of retina by cysts (P<0.001) in Pearson chi-square test. Fair agreement of 0.31 (P<0.001) between NIR-cR SLO and late FA leakage was found by the weighted kappa test. In regression analysis, NIR-cR SLO abnormality is highly correlated with outer and inner nuclear layers location of the cystic changes. Conclusions. The size of cysts and involved layers affect presenting features of SW-AF and NIR reflectance.http://dx.doi.org/10.1155/2022/6831396 |
| spellingShingle | Fariba Ghassemi Fatemeh Bazvand Houshang Faghihi Ramak Roohipourmoallai Maryam Masoumi Sepide Jamali Masoumeh Mohebbi Siamak Sabour Near-Infrared Confocal Reflectance Scanning Laser Ophthalmoscopy (SLO) and Short-Wavelength Autofluorescence Imaging in Cystic Diabetic Macular Edema Journal of Ophthalmology |
| title | Near-Infrared Confocal Reflectance Scanning Laser Ophthalmoscopy (SLO) and Short-Wavelength Autofluorescence Imaging in Cystic Diabetic Macular Edema |
| title_full | Near-Infrared Confocal Reflectance Scanning Laser Ophthalmoscopy (SLO) and Short-Wavelength Autofluorescence Imaging in Cystic Diabetic Macular Edema |
| title_fullStr | Near-Infrared Confocal Reflectance Scanning Laser Ophthalmoscopy (SLO) and Short-Wavelength Autofluorescence Imaging in Cystic Diabetic Macular Edema |
| title_full_unstemmed | Near-Infrared Confocal Reflectance Scanning Laser Ophthalmoscopy (SLO) and Short-Wavelength Autofluorescence Imaging in Cystic Diabetic Macular Edema |
| title_short | Near-Infrared Confocal Reflectance Scanning Laser Ophthalmoscopy (SLO) and Short-Wavelength Autofluorescence Imaging in Cystic Diabetic Macular Edema |
| title_sort | near infrared confocal reflectance scanning laser ophthalmoscopy slo and short wavelength autofluorescence imaging in cystic diabetic macular edema |
| url | http://dx.doi.org/10.1155/2022/6831396 |
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