Antithrombotic Management of Atrial Fibrillation Patients Presenting with Coronary Artery Disease: A Consensus Document of the Chinese Society of Cardiology

Abstract. The coexistence of coronary artery disease (CAD) and atrial fibrillation (AF) is common in clinical practice. Patients with CAD require antiplatelet therapy to reduce the occurrence of myocardial ischemic events. However, patients with AF at high risk of thromboembolism require oral antico...

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Main Authors: Chinese Society of Cardiology of Chinese Medical Association, Editorial Board of Chinese Journal of Cardiology, Xiaoxia Fu, Tianyu Xu.
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2021-03-01
Series:Cardiology Discovery
Online Access:http://journals.lww.com/10.1097/CD9.0000000000000020
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author Chinese Society of Cardiology of Chinese Medical Association, Editorial Board of Chinese Journal of Cardiology
Xiaoxia Fu
Tianyu Xu.
author_facet Chinese Society of Cardiology of Chinese Medical Association, Editorial Board of Chinese Journal of Cardiology
Xiaoxia Fu
Tianyu Xu.
author_sort Chinese Society of Cardiology of Chinese Medical Association, Editorial Board of Chinese Journal of Cardiology
collection DOAJ
description Abstract. The coexistence of coronary artery disease (CAD) and atrial fibrillation (AF) is common in clinical practice. Patients with CAD require antiplatelet therapy to reduce the occurrence of myocardial ischemic events. However, patients with AF at high risk of thromboembolism require oral anticoagulants to reduce the occurrence of thromboembolic events such as stroke. In cases where CAD coexists with AF, the combined use of antiplatelet and anticoagulation therapy can effectively reduce the risk of ischemic and thromboembolic events but increase the risk of bleeding at the same time. The optimal antithrombotic regimen in patients with both CAD and AF has been controversial in clinical practice. In recent years, the expert consensuses on antithrombotic therapy in patients with AF presenting with acute coronary syndrome and/or undergoing percutaneous coronary intervention have been successively released in Europe and North America, and have been updated in a timely manner. In contrast, the guidelines on antithrombotic therapies in China are lacking. Based on published clinical evidence, this consensus incorporated relevant international and Chinese guidelines, consensuses, and expert recommendations, and addressed the issues encountered in the clinical practice of antithrombotic therapy in patients with AF and different types of CAD. The current guideline is of great significance to guide treatment in patients with both CAD and AF in China.
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spelling doaj-art-6480213be3a14a44b5d961a5fbc8158a2025-08-20T02:07:57ZengWolters Kluwer Health/LWWCardiology Discovery2096-952X2693-84992021-03-0111152810.1097/CD9.0000000000000020202103000-00011Antithrombotic Management of Atrial Fibrillation Patients Presenting with Coronary Artery Disease: A Consensus Document of the Chinese Society of CardiologyChinese Society of Cardiology of Chinese Medical Association, Editorial Board of Chinese Journal of CardiologyXiaoxia FuTianyu Xu.Abstract. The coexistence of coronary artery disease (CAD) and atrial fibrillation (AF) is common in clinical practice. Patients with CAD require antiplatelet therapy to reduce the occurrence of myocardial ischemic events. However, patients with AF at high risk of thromboembolism require oral anticoagulants to reduce the occurrence of thromboembolic events such as stroke. In cases where CAD coexists with AF, the combined use of antiplatelet and anticoagulation therapy can effectively reduce the risk of ischemic and thromboembolic events but increase the risk of bleeding at the same time. The optimal antithrombotic regimen in patients with both CAD and AF has been controversial in clinical practice. In recent years, the expert consensuses on antithrombotic therapy in patients with AF presenting with acute coronary syndrome and/or undergoing percutaneous coronary intervention have been successively released in Europe and North America, and have been updated in a timely manner. In contrast, the guidelines on antithrombotic therapies in China are lacking. Based on published clinical evidence, this consensus incorporated relevant international and Chinese guidelines, consensuses, and expert recommendations, and addressed the issues encountered in the clinical practice of antithrombotic therapy in patients with AF and different types of CAD. The current guideline is of great significance to guide treatment in patients with both CAD and AF in China.http://journals.lww.com/10.1097/CD9.0000000000000020
spellingShingle Chinese Society of Cardiology of Chinese Medical Association, Editorial Board of Chinese Journal of Cardiology
Xiaoxia Fu
Tianyu Xu.
Antithrombotic Management of Atrial Fibrillation Patients Presenting with Coronary Artery Disease: A Consensus Document of the Chinese Society of Cardiology
Cardiology Discovery
title Antithrombotic Management of Atrial Fibrillation Patients Presenting with Coronary Artery Disease: A Consensus Document of the Chinese Society of Cardiology
title_full Antithrombotic Management of Atrial Fibrillation Patients Presenting with Coronary Artery Disease: A Consensus Document of the Chinese Society of Cardiology
title_fullStr Antithrombotic Management of Atrial Fibrillation Patients Presenting with Coronary Artery Disease: A Consensus Document of the Chinese Society of Cardiology
title_full_unstemmed Antithrombotic Management of Atrial Fibrillation Patients Presenting with Coronary Artery Disease: A Consensus Document of the Chinese Society of Cardiology
title_short Antithrombotic Management of Atrial Fibrillation Patients Presenting with Coronary Artery Disease: A Consensus Document of the Chinese Society of Cardiology
title_sort antithrombotic management of atrial fibrillation patients presenting with coronary artery disease a consensus document of the chinese society of cardiology
url http://journals.lww.com/10.1097/CD9.0000000000000020
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AT xiaoxiafu antithromboticmanagementofatrialfibrillationpatientspresentingwithcoronaryarterydiseaseaconsensusdocumentofthechinesesocietyofcardiology
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