Current considerations on Helicobacter pylori infection in children: A comprehensive review of the available evidence

Infection with Helicobacter pylori (H. pylori) is usually acquired in childhood. The prevalence of H. pylori is largely related to socioeconomic status and living conditions, especially those characterized by overcrowding and poor hygiene, with a high rate of intrafamilial transmission. Despite the...

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Main Authors: M. Rogalidou, A. Papadopoulou
Format: Article
Language:English
Published: Verduci Editore 2024-09-01
Series:Microbiota in Health and Disease
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Online Access:https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/09/e1034.pdf
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author M. Rogalidou
A. Papadopoulou
author_facet M. Rogalidou
A. Papadopoulou
author_sort M. Rogalidou
collection DOAJ
description Infection with Helicobacter pylori (H. pylori) is usually acquired in childhood. The prevalence of H. pylori is largely related to socioeconomic status and living conditions, especially those characterized by overcrowding and poor hygiene, with a high rate of intrafamilial transmission. Despite the global decline of H. pylori infection in most areas, prevalence remains high in some other areas. In children, severe disease associated with H. pylori infection is rare. Standard triple therapy, ideally prescribed according to susceptibility to H. pylori, is still the most commonly used form of therapy. The antibiotic resistance rate is high and probably the main cause of eradication failure. Several other factors are also being investigated for their influence on eradication rates. This review summarizes relevant publications on H. pylori infection in children from April 2023 to March 2024.
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series Microbiota in Health and Disease
spelling doaj-art-6476f367df45427bb59000fa74b6086a2025-01-03T10:30:12ZengVerduci EditoreMicrobiota in Health and Disease2704-88452024-09-01610.26355/mhd_20249_10341034Current considerations on Helicobacter pylori infection in children: A comprehensive review of the available evidenceM. Rogalidou0A. Papadopoulou1Division of Gastroenterology and Hepatology, First Department of Pediatrics, National and Kapodistrian University of Athens, Agia Sofia Children’s Hospital, Athens, GreeceDivision of Gastroenterology and Hepatology, First Department of Pediatrics, National and Kapodistrian University of Athens, Agia Sofia Children’s Hospital, Athens, GreeceInfection with Helicobacter pylori (H. pylori) is usually acquired in childhood. The prevalence of H. pylori is largely related to socioeconomic status and living conditions, especially those characterized by overcrowding and poor hygiene, with a high rate of intrafamilial transmission. Despite the global decline of H. pylori infection in most areas, prevalence remains high in some other areas. In children, severe disease associated with H. pylori infection is rare. Standard triple therapy, ideally prescribed according to susceptibility to H. pylori, is still the most commonly used form of therapy. The antibiotic resistance rate is high and probably the main cause of eradication failure. Several other factors are also being investigated for their influence on eradication rates. This review summarizes relevant publications on H. pylori infection in children from April 2023 to March 2024.https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/09/e1034.pdfh. pylorichildrenepidemiologyclinical manifestationsdiagnosistreatment.
spellingShingle M. Rogalidou
A. Papadopoulou
Current considerations on Helicobacter pylori infection in children: A comprehensive review of the available evidence
Microbiota in Health and Disease
h. pylori
children
epidemiology
clinical manifestations
diagnosis
treatment.
title Current considerations on Helicobacter pylori infection in children: A comprehensive review of the available evidence
title_full Current considerations on Helicobacter pylori infection in children: A comprehensive review of the available evidence
title_fullStr Current considerations on Helicobacter pylori infection in children: A comprehensive review of the available evidence
title_full_unstemmed Current considerations on Helicobacter pylori infection in children: A comprehensive review of the available evidence
title_short Current considerations on Helicobacter pylori infection in children: A comprehensive review of the available evidence
title_sort current considerations on helicobacter pylori infection in children a comprehensive review of the available evidence
topic h. pylori
children
epidemiology
clinical manifestations
diagnosis
treatment.
url https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/09/e1034.pdf
work_keys_str_mv AT mrogalidou currentconsiderationsonhelicobacterpyloriinfectioninchildrenacomprehensivereviewoftheavailableevidence
AT apapadopoulou currentconsiderationsonhelicobacterpyloriinfectioninchildrenacomprehensivereviewoftheavailableevidence