High-Risk PNPLA3 rs738409 Genotype Is Associated with Higher Concentrations of CCL2 in Liver Transplant Candidates with Alcoholic End-Stage Liver Disease

High-Risk PNPLA3 rs738409 Genotype Is Associated with Higher Concentrations of CCL2 in Liver Transplant Candidates with Alcoholic End-Stage Liver Disease

<i>Background and Objectives</i>: Patients with GG rs738409 patatin-like phospholipase domain-containing protein 3 (PNPLA3) genotype (148M variant) have greater risk to develop end-stage liver disease and its associated clinical complications, including hepatocellular carcinoma (HCC). We...

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Main Authors: Ivan Budimir Bekan, Dino Šisl, Alan Šućur, Ana Bainrauch, Valerija Bralić Lang, Pavao Planinić, Nataša Kovačić, Danka Grčević, Anna Mrzljak, Tomislav Kelava
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Medicina
Subjects:
cytokine
alcoholic liver disease
single nucleotide polymorphism
liver transplantation
PNPLA3 148M
chemokine (C-C motif) ligand 2
Online Access:https://www.mdpi.com/1648-9144/61/7/1293
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