Role of miR-181c in Diet-induced obesity through regulation of lipid synthesis in liver.

We recently identified a nuclear-encoded miRNA (miR-181c) in cardiomyocytes that can translocate into mitochondria to regulate mitochondrial gene mt-COX1 and influence obesity-induced cardiac dysfunction through the mitochondrial pathway. Because liver plays a pivotal role during obesity, we hypothe...

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Main Authors: Kei Akiyoshi, Gretha J Boersma, Miranda D Johnson, Fernanda Carrizo Velasquez, Brittany Dunkerly-Eyring, Shannon O'Brien, Atsushi Yamaguchi, Charles Steenbergen, Kellie L K Tamashiro, Samarjit Das
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0256973&type=printable
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