Proteome‐Wide Mendelian Randomization Identifies Natriuretic Peptide‐B and Novel Proteins as Potential Regulators of Pulse Pressure in Humans

Proteome‐Wide Mendelian Randomization Identifies Natriuretic Peptide‐B and Novel Proteins as Potential Regulators of Pulse Pressure in Humans

Background Large‐artery stiffness (LAS) significantly contributes to cardiovascular morbidity and death and is characterized by increased pulse pressure (PP). The biology underlying large‐artery stiffness in humans remains incompletely understood. Methods and Results We investigated associations bet...

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Bibliographic Details
Main Authors:	Marie‐Joe Dib, Devendra Meena, James Yarmolinsky, Joe D. Azzo, Oday Salman, Hamed Tavolinejad, Sushrima Gan, Cameron Beeche, Bianca Pourmussa, Dipender Gill, Stephen Burgess, Julio A. Chirinos
Format:	Article
Language:	English
Published:	Wiley 2025-08-01
Series:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:	arterial stiffness Mendelian randomization proteomics pulse pressure
Online Access:	https://www.ahajournals.org/doi/10.1161/JAHA.124.037596
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