Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation
Apoptosis is the main cause of atresia in ovarian follicles. In oxidative stress (OS) conditions, an imbalance between pro-apoptotic and anti-apoptotic genes can increase the apoptosis rate. In some diseases, such as cancers, patients lose fertility due to chemotherapy and radiotherapy. One way to m...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2024-05-01
|
| Series: | ImmunoAnalysis |
| Subjects: | |
| Online Access: | https://ia.tbzmed.ac.ir/PDF/ia-4-2.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850184488410152960 |
|---|---|
| author | Mahsa Rezaei Zarnaghi Zahra Bahroudi Melika Izadpanah Abbas Majdi Seghinsara Ali Abedelahi |
| author_facet | Mahsa Rezaei Zarnaghi Zahra Bahroudi Melika Izadpanah Abbas Majdi Seghinsara Ali Abedelahi |
| author_sort | Mahsa Rezaei Zarnaghi |
| collection | DOAJ |
| description | Apoptosis is the main cause of atresia in ovarian follicles. In oxidative stress (OS) conditions, an imbalance between pro-apoptotic and anti-apoptotic genes can increase the apoptosis rate. In some diseases, such as cancers, patients lose fertility due to chemotherapy and radiotherapy. One way to maintain fertility in these patients is ovarian tissue cryopreservation and transplantation (OTC/T). Studies show that OTC/T also increases apoptosis due to hypoxia and ischemia but fortunately new findings show that applying new approaches could decrease apoptosis in these procedures considerably. This article reviewed follicular atresia, apoptosis during cryopreservation and transplantation, and factors affecting the reduction of apoptosis. |
| format | Article |
| id | doaj-art-644349bb246f4d4baff11ca0282dccb6 |
| institution | OA Journals |
| issn | 2783-2589 |
| language | English |
| publishDate | 2024-05-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | ImmunoAnalysis |
| spelling | doaj-art-644349bb246f4d4baff11ca0282dccb62025-08-20T02:17:01ZengTabriz University of Medical SciencesImmunoAnalysis2783-25892024-05-01412210.34172/ia.4055ia-4055Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and TransplantationMahsa Rezaei Zarnaghi0Zahra Bahroudi1Melika Izadpanah2Abbas Majdi Seghinsara3Ali Abedelahi4Department of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranApoptosis is the main cause of atresia in ovarian follicles. In oxidative stress (OS) conditions, an imbalance between pro-apoptotic and anti-apoptotic genes can increase the apoptosis rate. In some diseases, such as cancers, patients lose fertility due to chemotherapy and radiotherapy. One way to maintain fertility in these patients is ovarian tissue cryopreservation and transplantation (OTC/T). Studies show that OTC/T also increases apoptosis due to hypoxia and ischemia but fortunately new findings show that applying new approaches could decrease apoptosis in these procedures considerably. This article reviewed follicular atresia, apoptosis during cryopreservation and transplantation, and factors affecting the reduction of apoptosis.https://ia.tbzmed.ac.ir/PDF/ia-4-2.pdfovarian transplantationapoptosisovarian cryopreservationantioxidantcell therapy |
| spellingShingle | Mahsa Rezaei Zarnaghi Zahra Bahroudi Melika Izadpanah Abbas Majdi Seghinsara Ali Abedelahi Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation ImmunoAnalysis ovarian transplantation apoptosis ovarian cryopreservation antioxidant cell therapy |
| title | Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation |
| title_full | Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation |
| title_fullStr | Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation |
| title_full_unstemmed | Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation |
| title_short | Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation |
| title_sort | novel approaches used for decreasing apoptosis rate in ovarian tissue cryopreservation and transplantation |
| topic | ovarian transplantation apoptosis ovarian cryopreservation antioxidant cell therapy |
| url | https://ia.tbzmed.ac.ir/PDF/ia-4-2.pdf |
| work_keys_str_mv | AT mahsarezaeizarnaghi novelapproachesusedfordecreasingapoptosisrateinovariantissuecryopreservationandtransplantation AT zahrabahroudi novelapproachesusedfordecreasingapoptosisrateinovariantissuecryopreservationandtransplantation AT melikaizadpanah novelapproachesusedfordecreasingapoptosisrateinovariantissuecryopreservationandtransplantation AT abbasmajdiseghinsara novelapproachesusedfordecreasingapoptosisrateinovariantissuecryopreservationandtransplantation AT aliabedelahi novelapproachesusedfordecreasingapoptosisrateinovariantissuecryopreservationandtransplantation |