Prevention of epiretinal membrane traction progression with topical indomethacin treatment: a case report and mini literature review

This case report explores the potential of 0.5% indomethacin eye drops (Indo0.5) in preventing the progression of epiretinal membrane traction. A 72-year-old patient with progressive vitreomacular traction was treated with Indo0.5, leading to a significant decrease in intraretinal cyst within 8 mont...

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Main Authors: Amedeo Lucente, Andrea Taloni, Federico Fava, Giuseppe Giannaccare
Format: Article
Language:English
Published: BioExcel Publishing Ltd 2025-06-01
Series:Drugs in Context
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Online Access:https://www.drugsincontext.com/prevention-of-epiretinal-membrane-traction-progression-with-topical-indomethacin-treatment-a-case-report-and-mini-literature-review/
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author Amedeo Lucente
Andrea Taloni
Federico Fava
Giuseppe Giannaccare
author_facet Amedeo Lucente
Andrea Taloni
Federico Fava
Giuseppe Giannaccare
author_sort Amedeo Lucente
collection DOAJ
description This case report explores the potential of 0.5% indomethacin eye drops (Indo0.5) in preventing the progression of epiretinal membrane traction. A 72-year-old patient with progressive vitreomacular traction was treated with Indo0.5, leading to a significant decrease in intraretinal cyst within 8 months, complete resorption after 16 months and full restoration of the retinal profile after 22 months. A mini literature review highlights the anti-inflammatory effects of indomethacin for various conditions affecting the anterior segment and suggests that the 0.5% concentration may also be effective in managing retinal inflammation. Indo0.5 could be a non-invasive option for slowing epiretinal membrane traction progression, supporting further research to optimize treatment strategies.
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institution Kabale University
issn 1740-4398
language English
publishDate 2025-06-01
publisher BioExcel Publishing Ltd
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series Drugs in Context
spelling doaj-art-6440d180e1ad4dcba83fd4f64f90d46a2025-08-20T03:27:44ZengBioExcel Publishing LtdDrugs in Context1740-43982025-06-011411110.7573/dic.2025-2-4Prevention of epiretinal membrane traction progression with topical indomethacin treatment: a case report and mini literature reviewAmedeo LucenteAndrea TaloniFederico FavaGiuseppe GiannaccareThis case report explores the potential of 0.5% indomethacin eye drops (Indo0.5) in preventing the progression of epiretinal membrane traction. A 72-year-old patient with progressive vitreomacular traction was treated with Indo0.5, leading to a significant decrease in intraretinal cyst within 8 months, complete resorption after 16 months and full restoration of the retinal profile after 22 months. A mini literature review highlights the anti-inflammatory effects of indomethacin for various conditions affecting the anterior segment and suggests that the 0.5% concentration may also be effective in managing retinal inflammation. Indo0.5 could be a non-invasive option for slowing epiretinal membrane traction progression, supporting further research to optimize treatment strategies.https://www.drugsincontext.com/prevention-of-epiretinal-membrane-traction-progression-with-topical-indomethacin-treatment-a-case-report-and-mini-literature-review/epiretinal membraneinflammation0.5% indomethacin eye dropsinternal limiting membranetraction of the epiretinal membrane
spellingShingle Amedeo Lucente
Andrea Taloni
Federico Fava
Giuseppe Giannaccare
Prevention of epiretinal membrane traction progression with topical indomethacin treatment: a case report and mini literature review
Drugs in Context
epiretinal membrane
inflammation
0.5% indomethacin eye drops
internal limiting membrane
traction of the epiretinal membrane
title Prevention of epiretinal membrane traction progression with topical indomethacin treatment: a case report and mini literature review
title_full Prevention of epiretinal membrane traction progression with topical indomethacin treatment: a case report and mini literature review
title_fullStr Prevention of epiretinal membrane traction progression with topical indomethacin treatment: a case report and mini literature review
title_full_unstemmed Prevention of epiretinal membrane traction progression with topical indomethacin treatment: a case report and mini literature review
title_short Prevention of epiretinal membrane traction progression with topical indomethacin treatment: a case report and mini literature review
title_sort prevention of epiretinal membrane traction progression with topical indomethacin treatment a case report and mini literature review
topic epiretinal membrane
inflammation
0.5% indomethacin eye drops
internal limiting membrane
traction of the epiretinal membrane
url https://www.drugsincontext.com/prevention-of-epiretinal-membrane-traction-progression-with-topical-indomethacin-treatment-a-case-report-and-mini-literature-review/
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AT federicofava preventionofepiretinalmembranetractionprogressionwithtopicalindomethacintreatmentacasereportandminiliteraturereview
AT giuseppegiannaccare preventionofepiretinalmembranetractionprogressionwithtopicalindomethacintreatmentacasereportandminiliteraturereview