Clinical features and outcomes of COVID-19 patients admitted at a tertiary hospital in Cebu City, Philippines
Introduction: The World Health Organization has categorized coronavirus disease 2019 (COVID-19) into mild, moderate, severe, and critical illness severities to guide clinical decision-making. This study aimed to describe the clinical characteristics, complications, and outcomes of COVID-19 patients...
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The Journal of Infection in Developing Countries
2022-05-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/15846 |
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| author | Mark Gavin Coronel Dinsay Maria Teresa Acosta Cañete Bryan Albert Tan Lim |
| author_facet | Mark Gavin Coronel Dinsay Maria Teresa Acosta Cañete Bryan Albert Tan Lim |
| author_sort | Mark Gavin Coronel Dinsay |
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Introduction: The World Health Organization has categorized coronavirus disease 2019 (COVID-19) into mild, moderate, severe, and critical illness severities to guide clinical decision-making. This study aimed to describe the clinical characteristics, complications, and outcomes of COVID-19 patients by illness severity, at a tertiary healthcare center in Cebu City, Philippines.
Methodology: This was a retrospective, observational cohort study that examined clinical information of patients with confirmed COVID-19 infection admitted between March and September 2020.
Results: Data from 901 admitted patients were analyzed, with 185 (20.5%) classified as mild, 429 (47.6%) as moderate, 223 (24.7%) as severe, and 64 (7.1%) as critical. The frequency of male gender, advancing age, co-morbidities (hypertension and diabetes mellitus), inflammatory marker elevation (LDH, CRP, Ferritin, Procalcitonin), and elevated mean white blood cell counts with relative neutrophilia and lymphopenia increased with COVID severity. Severe and critical cases of COVID presented with more diffuse lung involvement in chest radiographs and abnormal electrocardiographic patterns such as ischemic changes, PVCs, PACs, and sinus tachycardia. The most common complications on admission were ARDS (10.9%), AKI (10.1%), shock (6.6%), and cardiac arrest (6.3%). Mortality rates were highest in critical cases (82.8%). Severe and critical COVID-19 cases were predominant on final disposition, rising to 62.5% of the study population from 32.1% on admission.
Conclusions: This study highlights key differences in clinical characteristics, complications, and outcomes between illness severities. Risk prediction models are needed for disease progression and poor outcomes.
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| format | Article |
| id | doaj-art-643b583bcdba49588a895d4537cec0a9 |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2022-05-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-643b583bcdba49588a895d4537cec0a92025-08-20T03:52:39ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802022-05-01160510.3855/jidc.15846Clinical features and outcomes of COVID-19 patients admitted at a tertiary hospital in Cebu City, PhilippinesMark Gavin Coronel Dinsay0Maria Teresa Acosta Cañete1Bryan Albert Tan Lim2Department of Internal Medicine, Chong Hua Hospital, Cebu City, PhilippinesSection of Neurology, Chong Hua Hospital, Cebu City, PhilippinesSection of Infectious Diseases, Department of Internal Medicine, Chong Hua Hospital, Cebu City, Philippines Introduction: The World Health Organization has categorized coronavirus disease 2019 (COVID-19) into mild, moderate, severe, and critical illness severities to guide clinical decision-making. This study aimed to describe the clinical characteristics, complications, and outcomes of COVID-19 patients by illness severity, at a tertiary healthcare center in Cebu City, Philippines. Methodology: This was a retrospective, observational cohort study that examined clinical information of patients with confirmed COVID-19 infection admitted between March and September 2020. Results: Data from 901 admitted patients were analyzed, with 185 (20.5%) classified as mild, 429 (47.6%) as moderate, 223 (24.7%) as severe, and 64 (7.1%) as critical. The frequency of male gender, advancing age, co-morbidities (hypertension and diabetes mellitus), inflammatory marker elevation (LDH, CRP, Ferritin, Procalcitonin), and elevated mean white blood cell counts with relative neutrophilia and lymphopenia increased with COVID severity. Severe and critical cases of COVID presented with more diffuse lung involvement in chest radiographs and abnormal electrocardiographic patterns such as ischemic changes, PVCs, PACs, and sinus tachycardia. The most common complications on admission were ARDS (10.9%), AKI (10.1%), shock (6.6%), and cardiac arrest (6.3%). Mortality rates were highest in critical cases (82.8%). Severe and critical COVID-19 cases were predominant on final disposition, rising to 62.5% of the study population from 32.1% on admission. Conclusions: This study highlights key differences in clinical characteristics, complications, and outcomes between illness severities. Risk prediction models are needed for disease progression and poor outcomes. https://jidc.org/index.php/journal/article/view/15846COVID-19clinical featuresseverityPhilippines |
| spellingShingle | Mark Gavin Coronel Dinsay Maria Teresa Acosta Cañete Bryan Albert Tan Lim Clinical features and outcomes of COVID-19 patients admitted at a tertiary hospital in Cebu City, Philippines Journal of Infection in Developing Countries COVID-19 clinical features severity Philippines |
| title | Clinical features and outcomes of COVID-19 patients admitted at a tertiary hospital in Cebu City, Philippines |
| title_full | Clinical features and outcomes of COVID-19 patients admitted at a tertiary hospital in Cebu City, Philippines |
| title_fullStr | Clinical features and outcomes of COVID-19 patients admitted at a tertiary hospital in Cebu City, Philippines |
| title_full_unstemmed | Clinical features and outcomes of COVID-19 patients admitted at a tertiary hospital in Cebu City, Philippines |
| title_short | Clinical features and outcomes of COVID-19 patients admitted at a tertiary hospital in Cebu City, Philippines |
| title_sort | clinical features and outcomes of covid 19 patients admitted at a tertiary hospital in cebu city philippines |
| topic | COVID-19 clinical features severity Philippines |
| url | https://jidc.org/index.php/journal/article/view/15846 |
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