Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis

Purpose. To find if CHA2DS2-VASc scale can accurately predict the treatment, prognosis, and outcome for primary open-angle glaucoma (POAG). Patients and methods. A survey of 250,000 patient years was taken, using the records of the Ophthalmology Department at Ziv Medical Center. Data was collected r...

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Main Authors: Yoav Y. Pikkel, Daniel Krebs, Vadim Igal, Adi Sharabi-Nov, Irena Epstein, Joseph Pikkel
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2018/8931430
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author Yoav Y. Pikkel
Daniel Krebs
Vadim Igal
Adi Sharabi-Nov
Irena Epstein
Joseph Pikkel
author_facet Yoav Y. Pikkel
Daniel Krebs
Vadim Igal
Adi Sharabi-Nov
Irena Epstein
Joseph Pikkel
author_sort Yoav Y. Pikkel
collection DOAJ
description Purpose. To find if CHA2DS2-VASc scale can accurately predict the treatment, prognosis, and outcome for primary open-angle glaucoma (POAG). Patients and methods. A survey of 250,000 patient years was taken, using the records of the Ophthalmology Department at Ziv Medical Center. Data was collected regarding the retinal nerve fiber layer (RNFL), visual field (VF), line of treatment (LOT) of glaucoma, and all the data needed to accurately calculate CHA2DS2-VASc score for each patient. Results. Sixty-seven patients were included in the statistical analysis. The mean age was 72.5 years. The mean CHA2DS2-VASc score was 3.27 + −1.7. Positive Pearson’s correlation coefficients were found for LOT and CHA2DS2-VASc score, 0.35, and for RNFL grade and CHA2DS2-VASc score, 0.37. The correlation was negative for RNFL width and CHA2DS2-VASc score, −0.35. Conclusions. CHA2DS2-VASc score was shown to be correlated with glaucoma. This correlation was manifested positively by the LOT needed to stop glaucoma progression, with higher CHA2DS2-VASc scores correlated with more aggressive treatment. Since glaucoma is a disease with a progressing nature, it is important to treat patients aggressively on one hand, while offering the most benign treatment as possible on the other hand. Modification of the CHA2DS2-VASc score could achieve an even higher correlation.
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spelling doaj-art-6436aaad279240ecad383172ba2672172025-02-03T01:27:34ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/89314308931430Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and PrognosisYoav Y. Pikkel0Daniel Krebs1Vadim Igal2Adi Sharabi-Nov3Irena Epstein4Joseph Pikkel5Carmel Medical Center, Haifa, IsraelFaculty of Medicine, Bar-Ilan University, Safed, IsraelFaculty of Medicine, Bar-Ilan University, Safed, IsraelTel Hai Academic College, Kiryat Shmona, IsraelOphthalmology Department, Ziv Medical Center, Safed, IsraelFaculty of Medicine, Bar-Ilan University, Safed, IsraelPurpose. To find if CHA2DS2-VASc scale can accurately predict the treatment, prognosis, and outcome for primary open-angle glaucoma (POAG). Patients and methods. A survey of 250,000 patient years was taken, using the records of the Ophthalmology Department at Ziv Medical Center. Data was collected regarding the retinal nerve fiber layer (RNFL), visual field (VF), line of treatment (LOT) of glaucoma, and all the data needed to accurately calculate CHA2DS2-VASc score for each patient. Results. Sixty-seven patients were included in the statistical analysis. The mean age was 72.5 years. The mean CHA2DS2-VASc score was 3.27 + −1.7. Positive Pearson’s correlation coefficients were found for LOT and CHA2DS2-VASc score, 0.35, and for RNFL grade and CHA2DS2-VASc score, 0.37. The correlation was negative for RNFL width and CHA2DS2-VASc score, −0.35. Conclusions. CHA2DS2-VASc score was shown to be correlated with glaucoma. This correlation was manifested positively by the LOT needed to stop glaucoma progression, with higher CHA2DS2-VASc scores correlated with more aggressive treatment. Since glaucoma is a disease with a progressing nature, it is important to treat patients aggressively on one hand, while offering the most benign treatment as possible on the other hand. Modification of the CHA2DS2-VASc score could achieve an even higher correlation.http://dx.doi.org/10.1155/2018/8931430
spellingShingle Yoav Y. Pikkel
Daniel Krebs
Vadim Igal
Adi Sharabi-Nov
Irena Epstein
Joseph Pikkel
Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis
Journal of Ophthalmology
title Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis
title_full Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis
title_fullStr Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis
title_full_unstemmed Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis
title_short Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis
title_sort correlation between cha2ds2 vasc score and glaucoma treatment and prognosis
url http://dx.doi.org/10.1155/2018/8931430
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