Kounis Syndrome Secondary to Laxative Administration

Kounis syndrome (KS) is defined as an acute coronary syndrome triggered by the release of inflammatory mediators after an allergic attack. It usually occurs secondary to allergic injuries from foods, medications, and insect bites. However, there are no known reports of KS secondary to the intake of...

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Main Authors: Mateo Zuluaga-Gómez, Daniel González-Arroyave, Carlos M. Ardila
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2022/6087176
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author Mateo Zuluaga-Gómez
Daniel González-Arroyave
Carlos M. Ardila
author_facet Mateo Zuluaga-Gómez
Daniel González-Arroyave
Carlos M. Ardila
author_sort Mateo Zuluaga-Gómez
collection DOAJ
description Kounis syndrome (KS) is defined as an acute coronary syndrome triggered by the release of inflammatory mediators after an allergic attack. It usually occurs secondary to allergic injuries from foods, medications, and insect bites. However, there are no known reports of KS secondary to the intake of laxatives. This article reports the case of a 43-year-old woman who, after ingesting a dose of sodium phosphate monobasic/sodium phosphate dibasic, presented a maculopapular rash on the trunk and extremities. The electrocardiogram showed ST depression in V4-V5-V6 and signs of prolonged QTc; troponin I uptake was positive. Due to presumed myocardial injury and high suspicion of coronary disease, coronary angiography was requested, which showed epicardial coronary arteries, without angiographically significant stenosis, thus confirming the presence of KS secondary to the ingestion of a laxative.
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institution Kabale University
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series Case Reports in Medicine
spelling doaj-art-64304a3226c243e8804c054efbab46f82025-02-03T06:11:55ZengWileyCase Reports in Medicine1687-96352022-01-01202210.1155/2022/6087176Kounis Syndrome Secondary to Laxative AdministrationMateo Zuluaga-Gómez0Daniel González-Arroyave1Carlos M. Ardila2Hospital San Vicente FundaciónHospital San Vicente FundaciónUniversidad de AntioquiaKounis syndrome (KS) is defined as an acute coronary syndrome triggered by the release of inflammatory mediators after an allergic attack. It usually occurs secondary to allergic injuries from foods, medications, and insect bites. However, there are no known reports of KS secondary to the intake of laxatives. This article reports the case of a 43-year-old woman who, after ingesting a dose of sodium phosphate monobasic/sodium phosphate dibasic, presented a maculopapular rash on the trunk and extremities. The electrocardiogram showed ST depression in V4-V5-V6 and signs of prolonged QTc; troponin I uptake was positive. Due to presumed myocardial injury and high suspicion of coronary disease, coronary angiography was requested, which showed epicardial coronary arteries, without angiographically significant stenosis, thus confirming the presence of KS secondary to the ingestion of a laxative.http://dx.doi.org/10.1155/2022/6087176
spellingShingle Mateo Zuluaga-Gómez
Daniel González-Arroyave
Carlos M. Ardila
Kounis Syndrome Secondary to Laxative Administration
Case Reports in Medicine
title Kounis Syndrome Secondary to Laxative Administration
title_full Kounis Syndrome Secondary to Laxative Administration
title_fullStr Kounis Syndrome Secondary to Laxative Administration
title_full_unstemmed Kounis Syndrome Secondary to Laxative Administration
title_short Kounis Syndrome Secondary to Laxative Administration
title_sort kounis syndrome secondary to laxative administration
url http://dx.doi.org/10.1155/2022/6087176
work_keys_str_mv AT mateozuluagagomez kounissyndromesecondarytolaxativeadministration
AT danielgonzalezarroyave kounissyndromesecondarytolaxativeadministration
AT carlosmardila kounissyndromesecondarytolaxativeadministration