Biotherapeutic potentials of diverse probiotics of the Himalayan region: A Review

The highest ecosystems on Earth are located in India's Himalayan region, covering a distance of 3500 km from Jammu and Kashmir to Arunachal Pradesh in the northeastern part of the country. Limited information on the probiotic diversity within the traditional diets of the Western Himalaya is av...

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Main Authors: Nikita Bahuguna, Jigisha Anand, Divya Venugopal, Ankit Khanduri, Nishant Rai
Format: Article
Language:English
Published: Action for Sustainable Efficacious Development and Awareness 2025-01-01
Series:Environment Conservation Journal
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Online Access:https://journal.environcj.in/index.php/ecj/article/view/3155
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author Nikita Bahuguna
Jigisha Anand
Divya Venugopal
Ankit Khanduri
Nishant Rai
author_facet Nikita Bahuguna
Jigisha Anand
Divya Venugopal
Ankit Khanduri
Nishant Rai
author_sort Nikita Bahuguna
collection DOAJ
description The highest ecosystems on Earth are located in India's Himalayan region, covering a distance of 3500 km from Jammu and Kashmir to Arunachal Pradesh in the northeastern part of the country. Limited information on the probiotic diversity within the traditional diets of the Western Himalaya is available. Despite living in the challenging environment of high altitudes, the inhabitants of these areas display healthy and long lifespans, which are primarily attributed to their diet, particularly the traditional fermented foods. The potential for isolating native probiotic bacteria from traditional foods is, therefore, enormous. One of the main strategies for preventative treatment in humans may be to supplement the diet with nutrients that can shield against immune system problems and lower the risk of contracting illnesses like mycosis. The emergence of functional foods and nutraceuticals underscores the importance of reducing reliance on medications and increasing regular consumption of fermented foods. Researchers primarily suggest probiotics and lactic acid bacteria (LAB) as nutraceuticals due to their non-harmful effects on human health, their ability to activate the immune system, and their ability to enhance resistance to various illness situations. As per WHO, probiotic bacteria are defined as “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host.” Antifungal agents like azoles and amphotericin B are recommended as therapeutic agents as per the case. However, the emergence of drug-resistant strains worldwide has reduced the efficacy of these treatments. According to health organizations (national and international, including WHO), there is an urgent need to explore novel and alternative options, including probiotics. The current review highlights the biotherapeutic perspective of diverse probiotic strains, including next-generation probiotics against mycosis.
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spelling doaj-art-6415e4dc2a7c4d69a7007dce55ce26b92025-08-20T02:41:11ZengAction for Sustainable Efficacious Development and AwarenessEnvironment Conservation Journal0972-30992278-51242025-01-0126110.36953/ECJ.30203155Biotherapeutic potentials of diverse probiotics of the Himalayan region: A ReviewNikita Bahuguna0Jigisha Anand1Divya Venugopal2Ankit Khanduri3Nishant Rai 4Department of Microbiology, Graphic Era (Deemed to be University) Dehradun, Uttarakhand, IndiaDepartment of Biotechnology, Graphic Era (Deemed to be University) Dehradun, Uttarakhand, IndiaDepartment of Microbiology, Graphic Era (Deemed to be University) Dehradun, Uttarakhand, IndiaDepartment of Microbiology, Graphic Era Institute of Medical Sciences, Dehradun, Uttarakhand. IndiaDepartment of Biotechnology, Graphic Era (Deemed to be University) Dehradun, Uttarakhand, India The highest ecosystems on Earth are located in India's Himalayan region, covering a distance of 3500 km from Jammu and Kashmir to Arunachal Pradesh in the northeastern part of the country. Limited information on the probiotic diversity within the traditional diets of the Western Himalaya is available. Despite living in the challenging environment of high altitudes, the inhabitants of these areas display healthy and long lifespans, which are primarily attributed to their diet, particularly the traditional fermented foods. The potential for isolating native probiotic bacteria from traditional foods is, therefore, enormous. One of the main strategies for preventative treatment in humans may be to supplement the diet with nutrients that can shield against immune system problems and lower the risk of contracting illnesses like mycosis. The emergence of functional foods and nutraceuticals underscores the importance of reducing reliance on medications and increasing regular consumption of fermented foods. Researchers primarily suggest probiotics and lactic acid bacteria (LAB) as nutraceuticals due to their non-harmful effects on human health, their ability to activate the immune system, and their ability to enhance resistance to various illness situations. As per WHO, probiotic bacteria are defined as “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host.” Antifungal agents like azoles and amphotericin B are recommended as therapeutic agents as per the case. However, the emergence of drug-resistant strains worldwide has reduced the efficacy of these treatments. According to health organizations (national and international, including WHO), there is an urgent need to explore novel and alternative options, including probiotics. The current review highlights the biotherapeutic perspective of diverse probiotic strains, including next-generation probiotics against mycosis. https://journal.environcj.in/index.php/ecj/article/view/3155Candida sp.MycosisNext-generation probioticsProbiotic diversityTraditional foods
spellingShingle Nikita Bahuguna
Jigisha Anand
Divya Venugopal
Ankit Khanduri
Nishant Rai
Biotherapeutic potentials of diverse probiotics of the Himalayan region: A Review
Environment Conservation Journal
Candida sp.
Mycosis
Next-generation probiotics
Probiotic diversity
Traditional foods
title Biotherapeutic potentials of diverse probiotics of the Himalayan region: A Review
title_full Biotherapeutic potentials of diverse probiotics of the Himalayan region: A Review
title_fullStr Biotherapeutic potentials of diverse probiotics of the Himalayan region: A Review
title_full_unstemmed Biotherapeutic potentials of diverse probiotics of the Himalayan region: A Review
title_short Biotherapeutic potentials of diverse probiotics of the Himalayan region: A Review
title_sort biotherapeutic potentials of diverse probiotics of the himalayan region a review
topic Candida sp.
Mycosis
Next-generation probiotics
Probiotic diversity
Traditional foods
url https://journal.environcj.in/index.php/ecj/article/view/3155
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