The Diminution of R‐Loops Generated by LncRNA DSP‐AS1 Inhibits DSP Gene Transcription to Impede the Re‐Epithelialization During Diabetic Wound Healing

The Diminution of R‐Loops Generated by LncRNA DSP‐AS1 Inhibits DSP Gene Transcription to Impede the Re‐Epithelialization During Diabetic Wound Healing

Abstract Re‐epithelialization constitutes a critical stage in the intricate process of wound healing, yet its mechanisms in the context of diabetic wounds remain elusive. In this study, the role of the mesenchymal‐epithelial transition (MET) vis‐à‐vis the epithelial‐mesenchymal transition (EMT) of k...

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Main Authors: Chen Yang, Hong Lian, Hengli Luo, Chenlin Song, Jianghong Lin, Zhuoxian Liang, Yulin Yang, Xiaosi Hong, Shaohua Li, Yanbo Chen, Liangyan Wu, Li Yan, Sifan Chen, Meng Ren
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
anti‐sense lncRNAs
desmoplakin
diabetic wound healing
R‐loop
ten‐eleven translocation dioxygenase proteins
Online Access:https://doi.org/10.1002/advs.202406021
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