Dynamic Consistent NSFD Scheme for a Delayed Viral Infection Model with Immune Response and Nonlinear Incidence

In this paper, a discrete-time model has been proposed by applying nonstandard finite difference (NSFD) scheme to solve a delayed viral infection model with immune response and general nonlinear incidence. It is shown that the discrete model has equilibria which are exactly the same as those of the...

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Main Authors: Jinhu Xu, Yan Geng
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Discrete Dynamics in Nature and Society
Online Access:http://dx.doi.org/10.1155/2017/3141736
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author Jinhu Xu
Yan Geng
author_facet Jinhu Xu
Yan Geng
author_sort Jinhu Xu
collection DOAJ
description In this paper, a discrete-time model has been proposed by applying nonstandard finite difference (NSFD) scheme to solve a delayed viral infection model with immune response and general nonlinear incidence. It is shown that the discrete model has equilibria which are exactly the same as those of the original continuous model. Using discrete-time analogue of Lyapunov functionals, the global asymptotic stability of the equilibria of the discrete model is fully determined by the basic reproduction number of the virus and immune response, R0 and R1, with no restriction on the time step size, which implies that the NSFD scheme preserves the qualitative dynamics of the corresponding continuous model.
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institution Kabale University
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spelling doaj-art-63fb617bb6e94240b3aa0c5ccc0d76a32025-08-20T03:34:25ZengWileyDiscrete Dynamics in Nature and Society1026-02261607-887X2017-01-01201710.1155/2017/31417363141736Dynamic Consistent NSFD Scheme for a Delayed Viral Infection Model with Immune Response and Nonlinear IncidenceJinhu Xu0Yan Geng1Department of Applied Mathematics, Xi’an University of Technology, Xi’an 710048, ChinaSchool of Mathematics and Statistics, Xi’an Jiaotong University, Xi’an 710049, ChinaIn this paper, a discrete-time model has been proposed by applying nonstandard finite difference (NSFD) scheme to solve a delayed viral infection model with immune response and general nonlinear incidence. It is shown that the discrete model has equilibria which are exactly the same as those of the original continuous model. Using discrete-time analogue of Lyapunov functionals, the global asymptotic stability of the equilibria of the discrete model is fully determined by the basic reproduction number of the virus and immune response, R0 and R1, with no restriction on the time step size, which implies that the NSFD scheme preserves the qualitative dynamics of the corresponding continuous model.http://dx.doi.org/10.1155/2017/3141736
spellingShingle Jinhu Xu
Yan Geng
Dynamic Consistent NSFD Scheme for a Delayed Viral Infection Model with Immune Response and Nonlinear Incidence
Discrete Dynamics in Nature and Society
title Dynamic Consistent NSFD Scheme for a Delayed Viral Infection Model with Immune Response and Nonlinear Incidence
title_full Dynamic Consistent NSFD Scheme for a Delayed Viral Infection Model with Immune Response and Nonlinear Incidence
title_fullStr Dynamic Consistent NSFD Scheme for a Delayed Viral Infection Model with Immune Response and Nonlinear Incidence
title_full_unstemmed Dynamic Consistent NSFD Scheme for a Delayed Viral Infection Model with Immune Response and Nonlinear Incidence
title_short Dynamic Consistent NSFD Scheme for a Delayed Viral Infection Model with Immune Response and Nonlinear Incidence
title_sort dynamic consistent nsfd scheme for a delayed viral infection model with immune response and nonlinear incidence
url http://dx.doi.org/10.1155/2017/3141736
work_keys_str_mv AT jinhuxu dynamicconsistentnsfdschemeforadelayedviralinfectionmodelwithimmuneresponseandnonlinearincidence
AT yangeng dynamicconsistentnsfdschemeforadelayedviralinfectionmodelwithimmuneresponseandnonlinearincidence