Cytomegalovirus infection and immune-mediated inflammatory rheumatic diseases: what is known today

Cytomegalovirus (CMV) infection is a common viral anthroponotic infection characterized by a variety of clinical and laboratory symptoms. There is a growing body of data on the association between CMV and the development of immune-mediated inflammatory rheumatic diseases (IIRD). The presence of immu...

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Main Authors: B. S. Belov, N. V. Muravyova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2024-12-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/1661
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author B. S. Belov
N. V. Muravyova
author_facet B. S. Belov
N. V. Muravyova
author_sort B. S. Belov
collection DOAJ
description Cytomegalovirus (CMV) infection is a common viral anthroponotic infection characterized by a variety of clinical and laboratory symptoms. There is a growing body of data on the association between CMV and the development of immune-mediated inflammatory rheumatic diseases (IIRD). The presence of immunopathological disorders caused both by the disease itself and using drugs with immunosuppressive effect determines the relatively high prevalence of comorbid active CMV in patients with IIRD. The commonality of the clinical picture of CMV infection and individual IIRDs often leads to problems in the diagnosis and differentiation between these diseases. The lack of recommendations for the rational use of antiviral drugs for therapeutic and prophylactic purposes in IIRD calls for further research.
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series Современная ревматология
spelling doaj-art-63f8253a26d542a583e1560ca8d80bb32025-08-20T03:20:58ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2024-12-0118671310.14412/1996-7012-2024-6-7-132732Cytomegalovirus infection and immune-mediated inflammatory rheumatic diseases: what is known todayB. S. Belov0N. V. Muravyova1V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyCytomegalovirus (CMV) infection is a common viral anthroponotic infection characterized by a variety of clinical and laboratory symptoms. There is a growing body of data on the association between CMV and the development of immune-mediated inflammatory rheumatic diseases (IIRD). The presence of immunopathological disorders caused both by the disease itself and using drugs with immunosuppressive effect determines the relatively high prevalence of comorbid active CMV in patients with IIRD. The commonality of the clinical picture of CMV infection and individual IIRDs often leads to problems in the diagnosis and differentiation between these diseases. The lack of recommendations for the rational use of antiviral drugs for therapeutic and prophylactic purposes in IIRD calls for further research.https://mrj.ima-press.net/mrj/article/view/1661cytomegalovirus infectionimmune-inflammatory rheumatic diseasesmolecular mimicrybystander activationcomorbiditytreatmentprevention
spellingShingle B. S. Belov
N. V. Muravyova
Cytomegalovirus infection and immune-mediated inflammatory rheumatic diseases: what is known today
Современная ревматология
cytomegalovirus infection
immune-inflammatory rheumatic diseases
molecular mimicry
bystander activation
comorbidity
treatment
prevention
title Cytomegalovirus infection and immune-mediated inflammatory rheumatic diseases: what is known today
title_full Cytomegalovirus infection and immune-mediated inflammatory rheumatic diseases: what is known today
title_fullStr Cytomegalovirus infection and immune-mediated inflammatory rheumatic diseases: what is known today
title_full_unstemmed Cytomegalovirus infection and immune-mediated inflammatory rheumatic diseases: what is known today
title_short Cytomegalovirus infection and immune-mediated inflammatory rheumatic diseases: what is known today
title_sort cytomegalovirus infection and immune mediated inflammatory rheumatic diseases what is known today
topic cytomegalovirus infection
immune-inflammatory rheumatic diseases
molecular mimicry
bystander activation
comorbidity
treatment
prevention
url https://mrj.ima-press.net/mrj/article/view/1661
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