Breast cancer association with oncogenic papillomaviruses: arguments pro and con
Possible breast cancer (BC) association with oncogenic human papilloma viruses (HPV) remains subject for discussion. DNA of these viruses was found in numerous BC samples in predominant majority of researches into the problem, that being the main argument in favour of their involvement into genesis...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2023-04-01
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| Series: | Успехи молекулярной онкологии |
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| Online Access: | https://umo.abvpress.ru/jour/article/view/508 |
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| _version_ | 1849241258695852032 |
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| author | G. M. Volgareva |
| author_facet | G. M. Volgareva |
| author_sort | G. M. Volgareva |
| collection | DOAJ |
| description | Possible breast cancer (BC) association with oncogenic human papilloma viruses (HPV) remains subject for discussion. DNA of these viruses was found in numerous BC samples in predominant majority of researches into the problem, that being the main argument in favour of their involvement into genesis of the given tumor. The principal objection to the opinion is that the HPV genomes number per a single cancer cell in HPV-positive BC is several orders of magnitude inferior to the similar indicator for cervical cancer. Urgency of the issue of possible BC association with oncogenic HPVs increases under the development of effective preventive vaccines against HPV infection. To clarify this matter the data might help either confirming or disproving the oncogenic HPV genome activity in DNA HPV-positive BC. |
| format | Article |
| id | doaj-art-63edfa97c9724029914972c6cb86c6d2 |
| institution | Kabale University |
| issn | 2313-805X 2413-3787 |
| language | Russian |
| publishDate | 2023-04-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Успехи молекулярной онкологии |
| spelling | doaj-art-63edfa97c9724029914972c6cb86c6d22025-08-20T04:00:14ZrusABV-pressУспехи молекулярной онкологии2313-805X2413-37872023-04-01101182410.17650/2313-805X-2023-10-1-18-24269Breast cancer association with oncogenic papillomaviruses: arguments pro and conG. M. Volgareva0N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaPossible breast cancer (BC) association with oncogenic human papilloma viruses (HPV) remains subject for discussion. DNA of these viruses was found in numerous BC samples in predominant majority of researches into the problem, that being the main argument in favour of their involvement into genesis of the given tumor. The principal objection to the opinion is that the HPV genomes number per a single cancer cell in HPV-positive BC is several orders of magnitude inferior to the similar indicator for cervical cancer. Urgency of the issue of possible BC association with oncogenic HPVs increases under the development of effective preventive vaccines against HPV infection. To clarify this matter the data might help either confirming or disproving the oncogenic HPV genome activity in DNA HPV-positive BC.https://umo.abvpress.ru/jour/article/view/508breast canceroncogenic human papilloma virusesviral genome activity |
| spellingShingle | G. M. Volgareva Breast cancer association with oncogenic papillomaviruses: arguments pro and con Успехи молекулярной онкологии breast cancer oncogenic human papilloma viruses viral genome activity |
| title | Breast cancer association with oncogenic papillomaviruses: arguments pro and con |
| title_full | Breast cancer association with oncogenic papillomaviruses: arguments pro and con |
| title_fullStr | Breast cancer association with oncogenic papillomaviruses: arguments pro and con |
| title_full_unstemmed | Breast cancer association with oncogenic papillomaviruses: arguments pro and con |
| title_short | Breast cancer association with oncogenic papillomaviruses: arguments pro and con |
| title_sort | breast cancer association with oncogenic papillomaviruses arguments pro and con |
| topic | breast cancer oncogenic human papilloma viruses viral genome activity |
| url | https://umo.abvpress.ru/jour/article/view/508 |
| work_keys_str_mv | AT gmvolgareva breastcancerassociationwithoncogenicpapillomavirusesargumentsproandcon |