Method development and clinical validation of LAMP-CRISPR/Cas12a for rapid detection of respiratory pathogens in children

Method development and clinical validation of LAMP-CRISPR/Cas12a for rapid detection of respiratory pathogens in children

BackgroundRespiratory tract infections pose a substantial health burden, particularly among pediatric populations globally. The timely and accurate identification of pathogens such as Streptococcus pneumoniae (SP) and Mycoplasma pneumoniae (MP) is critical for effective clinical management.MethodsIn...

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Bibliographic Details
Main Authors: Siyan Zhou, Xin Zhao, Fanzheng Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pediatrics
Subjects:
respiratory tract infections
LAMP-CRISPR/Cas12a
streptococcus pneumoniae
mycoplasma pneumoniae
molecular diagnostics
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1533100/full
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