Michaelis-Menten kinetics, the operator-repressor system, and least squares approaches
The Michaelis-Menten (MM) function is a fractional linear function depending on two positive parameters.These can be estimated by nonlinear or linear least squares methods.The non-linear methods, based directly on the defect of the MM function, can fail and not produce any minimizer.The linear met...
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Main Author: | Karl Peter Hadeler |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2013-07-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.1541 |
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