Development of a High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS) Method to Determine the Presence of Rivastigmine in Human Plasma in Clinical Studies of Comparative Pharmacokinetics

Development of a High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS) Method to Determine the Presence of Rivastigmine in Human Plasma in Clinical Studies of Comparative Pharmacokinetics

The basis for conducting bioequivalence studies is the determination of the bioavailability of the active substance of the drug at its place of action by establishing the concentration of the drug in biological fluids using sensitive analytical techniques. The bioanalytical technique used should prov...

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Bibliographic Details
Main Authors: M. S. Dolov, L. A. Fishgoit, P. D. Sobolev, E. P. Tkach
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2023-02-01
Series:Антибиотики и Химиотерапия
Subjects:
rivastigmine
development of a hplc-ms/ms method
bioequivalence
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/991
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