A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient
Introduction: This brief picture-oriented case report focuses on typical skin lesions in a patient who developed Ecthyma gangrenosum and pseudomonal sepsis after extensive immunosuppressive therapy for Pemphigus vulgaris. Case presentation: The patient was immunosuppressed with high doses of gluc...
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The Journal of Infection in Developing Countries
2023-11-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/18040 |
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| author | Marija Tomanovic Vesna Reljic Jelena Peric Dubravka Zivanovic |
| author_facet | Marija Tomanovic Vesna Reljic Jelena Peric Dubravka Zivanovic |
| author_sort | Marija Tomanovic |
| collection | DOAJ |
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Introduction: This brief picture-oriented case report focuses on typical skin lesions in a patient who developed Ecthyma gangrenosum and pseudomonal sepsis after extensive immunosuppressive therapy for Pemphigus vulgaris.
Case presentation: The patient was immunosuppressed with high doses of glucocorticoids and azathioprine; the follow-up after the treatment was not carried out well due to the pandemic conditions and because the patient herself got a Covid infection, which resulted in the development of pseudomonal sepsis and Ecthyma gangrenosum. The outcome was fatal despite extensive broad-spectrum antibiotic therapy, plasmapheresis, and intravenous immunoglobulins.
Conclusions: Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients, because of multi-drug resistance in the first place.
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| format | Article |
| id | doaj-art-63cf38ecd9b44fbcbfe49a1cf7a1ec77 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2023-11-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-63cf38ecd9b44fbcbfe49a1cf7a1ec772025-08-20T02:27:07ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-11-01171110.3855/jidc.18040A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patientMarija Tomanovic0Vesna Reljic1Jelena Peric2Dubravka Zivanovic3Clinic of Dermatology and Venereology, University clinical center of Serbia, Belgrade, SerbiaClinic of Dermatology and Venereology, University clinical center of Serbia, Belgrade, SerbiaClinic of Dermatology and Venereology, University clinical center of Serbia, Belgrade, SerbiaClinic of Dermatology and Venereology, University clinical center of Serbia, Belgrade, Serbia Introduction: This brief picture-oriented case report focuses on typical skin lesions in a patient who developed Ecthyma gangrenosum and pseudomonal sepsis after extensive immunosuppressive therapy for Pemphigus vulgaris. Case presentation: The patient was immunosuppressed with high doses of glucocorticoids and azathioprine; the follow-up after the treatment was not carried out well due to the pandemic conditions and because the patient herself got a Covid infection, which resulted in the development of pseudomonal sepsis and Ecthyma gangrenosum. The outcome was fatal despite extensive broad-spectrum antibiotic therapy, plasmapheresis, and intravenous immunoglobulins. Conclusions: Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients, because of multi-drug resistance in the first place. https://jidc.org/index.php/journal/article/view/18040Ecthyma gangrenosumPseudomonas aeruginosasepsisimmunocompromisedPemphigus vulgaris |
| spellingShingle | Marija Tomanovic Vesna Reljic Jelena Peric Dubravka Zivanovic A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient Journal of Infection in Developing Countries Ecthyma gangrenosum Pseudomonas aeruginosa sepsis immunocompromised Pemphigus vulgaris |
| title | A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient |
| title_full | A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient |
| title_fullStr | A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient |
| title_full_unstemmed | A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient |
| title_short | A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient |
| title_sort | fatal case of ecthyma gangrenosum in a critically ill and immunocompromised patient |
| topic | Ecthyma gangrenosum Pseudomonas aeruginosa sepsis immunocompromised Pemphigus vulgaris |
| url | https://jidc.org/index.php/journal/article/view/18040 |
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