A Semi-Micro Extraction Spectrophotometric Determination of Iron Using 4-Nitrocatechol and Xylometazoline Hydrochloride
A chromogenic solvent extraction system for Fe(III) based on 4-nitrocatechol (4NC) and xylometazoline hydrochloride (XMH) was investigated. The optimum conditions for extraction spectrophotometric determination of iron were found. Under these conditions, the formula of the extracted complex was (XMH...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-02-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/30/4/899 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | A chromogenic solvent extraction system for Fe(III) based on 4-nitrocatechol (4NC) and xylometazoline hydrochloride (XMH) was investigated. The optimum conditions for extraction spectrophotometric determination of iron were found. Under these conditions, the formula of the extracted complex was (XMH<sup>+</sup>)<sub>3</sub>[Fe(4NC)<sub>3</sub>] and the apparent molar absorption coefficient at <i>λ</i><sub>max</sub> = 464 nm was 1.9 × 10<sup>5</sup> dm<sup>3</sup> mol<sup>−1</sup> cm<sup>−1</sup> (4-fold enrichment). To validate the aforementioned formula and gather information about the spin state of the central Fe(III) ion, a combined experimental-theoretical approach was employed. This approach entailed the experimental determination of the 4NC:Fe and XMH:Fe molar ratios and the optimization of potential color-bearing structures utilizing the B3LYP/6-311G computational chemistry method. The effect of foreign ions was thoroughly examined, and a sensitive, simple, and inexpensive analytical procedure was proposed, which was successfully applied for determining iron in pharmaceutical and industrial samples. |
|---|---|
| ISSN: | 1420-3049 |