Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore

Abstract Objectives This study seeks to evaluate the imaging characteristics and patient outcomes from the imaging recommendations of the ACR Appropriateness Criteria (AC), the ESR iGuide, and RCR iRefer. Materials and methods This retrospective study evaluated cervical spine X-rays and CTs performe...

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Main Authors: Yi Xiang Tay, Shane J. Foley, Ronan Killeen, Marcus E. H. Ong, Robert Chun Chen, Lai Peng Chan, Eu Jin Tan, May San Mak, Wenlu Hou, Jonathan P. McNulty
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:Insights into Imaging
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Online Access:https://doi.org/10.1186/s13244-025-02048-9
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author Yi Xiang Tay
Shane J. Foley
Ronan Killeen
Marcus E. H. Ong
Robert Chun Chen
Lai Peng Chan
Eu Jin Tan
May San Mak
Wenlu Hou
Jonathan P. McNulty
author_facet Yi Xiang Tay
Shane J. Foley
Ronan Killeen
Marcus E. H. Ong
Robert Chun Chen
Lai Peng Chan
Eu Jin Tan
May San Mak
Wenlu Hou
Jonathan P. McNulty
author_sort Yi Xiang Tay
collection DOAJ
description Abstract Objectives This study seeks to evaluate the imaging characteristics and patient outcomes from the imaging recommendations of the ACR Appropriateness Criteria (AC), the ESR iGuide, and RCR iRefer. Materials and methods This retrospective study evaluated cervical spine X-rays and CTs performed consecutively in a Singapore emergency department (ED) between October 1st and December 31st, 2022. Patient demographics, clinical diagnosis, ED clinical notes, and radiological findings were extracted from the electronic health record and subsequently reviewed to determine the associated imaging recommendations. Results 452 (mean age, 56 ± 17.3 years, 54.9% female) and 153 (mean age, 52.8 ± 21.4 years, 65.4% male) patients underwent X-ray and CT cervical spine, respectively. According to ACR AC and ESR iGuide, the positivity rate (4.3–7.2%) was the highest for appropriate studies and the lowest (0%) for inappropriate studies. For RCR iRefer, positivity rates (1.1–7.0%) were only observed for imaging classified as “Indicated only in specific circumstances”. There was a minimal difference in the proportion of patients with radiological findings that were categorised as positive and negative across the recommendations from the three guidelines. Most patients with inappropriate imaging in the X-ray cohort were discharged home or referred to specialists, whereas those in the CT cohort were primarily admitted to the hospital for conditions unrelated to the cervical spine. Conclusions Inappropriate cervical spine imaging was associated with a lack of positive, significant findings. Imaging referral guidelines are specific and can effectively rule out significant pathology when imaging in the ED is not indicated. Clinical practice in the ED must incorporate imaging referral guidelines. Critical relevance statement Imaging referral guidelines were effective in excluding a positive finding in traumatic and non-traumatic patients, especially when aligned with evidence-based clinical criteria. Key Points There are numerous imaging referral guidelines with unique methodologies, but the impact of individual imaging recommendations on imaging characteristics and patient dispositions remains unclear. There is minimal difference in the positivity rates across individual imaging recommendations from all three imaging referral guidelines. Inappropriate cervical spine imaging was associated with a lack of positive, significant findings. Guidelines are still effective in excluding significant pathology when imaging is not indicated Graphical Abstract
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spelling doaj-art-63ccc8ee53174f7fa050bd30f7d470cb2025-08-20T03:46:03ZengSpringerOpenInsights into Imaging1869-41012025-08-0116111010.1186/s13244-025-02048-9Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in SingaporeYi Xiang Tay0Shane J. Foley1Ronan Killeen2Marcus E. H. Ong3Robert Chun Chen4Lai Peng Chan5Eu Jin Tan6May San Mak7Wenlu Hou8Jonathan P. McNulty9Radiography and Diagnostic Imaging, School of Medicine, University College DublinRadiography and Diagnostic Imaging, School of Medicine, University College DublinSt Vincent’s University HospitalDepartment of Emergency Medicine, Division of Medicine, Singapore General HospitalDuke-NUS Graduate Medical SchoolDuke-NUS Graduate Medical SchoolDuke-NUS Graduate Medical SchoolDuke-NUS Graduate Medical SchoolDuke-NUS Graduate Medical SchoolRadiography and Diagnostic Imaging, School of Medicine, University College DublinAbstract Objectives This study seeks to evaluate the imaging characteristics and patient outcomes from the imaging recommendations of the ACR Appropriateness Criteria (AC), the ESR iGuide, and RCR iRefer. Materials and methods This retrospective study evaluated cervical spine X-rays and CTs performed consecutively in a Singapore emergency department (ED) between October 1st and December 31st, 2022. Patient demographics, clinical diagnosis, ED clinical notes, and radiological findings were extracted from the electronic health record and subsequently reviewed to determine the associated imaging recommendations. Results 452 (mean age, 56 ± 17.3 years, 54.9% female) and 153 (mean age, 52.8 ± 21.4 years, 65.4% male) patients underwent X-ray and CT cervical spine, respectively. According to ACR AC and ESR iGuide, the positivity rate (4.3–7.2%) was the highest for appropriate studies and the lowest (0%) for inappropriate studies. For RCR iRefer, positivity rates (1.1–7.0%) were only observed for imaging classified as “Indicated only in specific circumstances”. There was a minimal difference in the proportion of patients with radiological findings that were categorised as positive and negative across the recommendations from the three guidelines. Most patients with inappropriate imaging in the X-ray cohort were discharged home or referred to specialists, whereas those in the CT cohort were primarily admitted to the hospital for conditions unrelated to the cervical spine. Conclusions Inappropriate cervical spine imaging was associated with a lack of positive, significant findings. Imaging referral guidelines are specific and can effectively rule out significant pathology when imaging in the ED is not indicated. Clinical practice in the ED must incorporate imaging referral guidelines. Critical relevance statement Imaging referral guidelines were effective in excluding a positive finding in traumatic and non-traumatic patients, especially when aligned with evidence-based clinical criteria. Key Points There are numerous imaging referral guidelines with unique methodologies, but the impact of individual imaging recommendations on imaging characteristics and patient dispositions remains unclear. There is minimal difference in the positivity rates across individual imaging recommendations from all three imaging referral guidelines. Inappropriate cervical spine imaging was associated with a lack of positive, significant findings. Guidelines are still effective in excluding significant pathology when imaging is not indicated Graphical Abstracthttps://doi.org/10.1186/s13244-025-02048-9Evidence-based practiceClinical decision-makingValue-based health careRadiologyDiagnostic imaging
spellingShingle Yi Xiang Tay
Shane J. Foley
Ronan Killeen
Marcus E. H. Ong
Robert Chun Chen
Lai Peng Chan
Eu Jin Tan
May San Mak
Wenlu Hou
Jonathan P. McNulty
Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore
Insights into Imaging
Evidence-based practice
Clinical decision-making
Value-based health care
Radiology
Diagnostic imaging
title Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore
title_full Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore
title_fullStr Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore
title_full_unstemmed Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore
title_short Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore
title_sort positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in singapore
topic Evidence-based practice
Clinical decision-making
Value-based health care
Radiology
Diagnostic imaging
url https://doi.org/10.1186/s13244-025-02048-9
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