Suppressive effects of Momordica charantia MAP30 on the senescence, proliferation and migration of bladder cancer cells mediated by CENPA

Suppressive effects of Momordica charantia MAP30 on the senescence, proliferation and migration of bladder cancer cells mediated by CENPA

Abstract Bladder cancer (BC) is notably prevalent, particularly among men. Emerging evidence highlights that traditional Chinese medicine (TCM) has distinct anticancer properties. This study focuses on recombinant MAP30, a key active constituent of Momordica charantia extract, recognized for its ant...

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Bibliographic Details
Main Authors: Kun Lu, Liu Chao, Jin Wang, Xiangyu Wang, Longjun Cai, Jianjun Zhang, Shaoqi Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Momordica charantia
MAP30
Cell senescence
CENPA
Traditional Chinese medicine
Online Access:https://doi.org/10.1038/s41598-025-14977-y
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