Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban Space
Abstract Airborne viruses are ubiquitous and play critical roles in maintaining ecosystem balance, however, they remain unexplored. Here, it is aimed to demonstrate that highly diverse airborne viromes carry out specific metabolic functions and use different transmission modes under different air qu...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-12-01
|
| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202404512 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850062131372752896 |
|---|---|
| author | Aihua Deng Junyue Wang Lai Li Ruilin Shi Xuemin Li Tingyi Wen |
| author_facet | Aihua Deng Junyue Wang Lai Li Ruilin Shi Xuemin Li Tingyi Wen |
| author_sort | Aihua Deng |
| collection | DOAJ |
| description | Abstract Airborne viruses are ubiquitous and play critical roles in maintaining ecosystem balance, however, they remain unexplored. Here, it is aimed to demonstrate that highly diverse airborne viromes carry out specific metabolic functions and use different transmission modes under different air quality conditions. A total of 263.5‐Gb data are collected from 13 air samples for viral metagenomic analysis. After assembly and curation, a total of 12 484 viral contigs (1.5–184.2 kb) are assigned to 221 genus‐level clades belonging to 47 families, 19 orders, and 15 classes. The composition of viral communities is influenced by weather conditions, with the main biomarker being Caudoviricetes. The most dominant viruses in these air samples belong to the dsDNA Caudoviricetes (54.0%) and ssDNA Repensiviricetes (31.2%) classes. Twelve novel candidate viruses are identified at the order/family/genus levels by alignment of complete genomes and core genes. Notably, Caudoviricetes are highly prevalent in cloudy and smoggy air, whereas Repensiviricetes are highly dominant in sunny and rainy air. Diverse auxiliary metabolic genes of airborne viruses are mainly involved in deoxynucleotide synthesis, implying their unique roles in atmosphere ecosystem. These findings deepen the understanding of the meteorological impacts on viral composition, transmission mode, and ecological roles in the air that we breathe. |
| format | Article |
| id | doaj-art-63c95498aaa147bb8e956fc491768cde |
| institution | DOAJ |
| issn | 2198-3844 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj-art-63c95498aaa147bb8e956fc491768cde2025-08-20T02:50:00ZengWileyAdvanced Science2198-38442024-12-011146n/an/a10.1002/advs.202404512Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban SpaceAihua Deng0Junyue Wang1Lai Li2Ruilin Shi3Xuemin Li4Tingyi Wen5State Key Laboratory of Animal Nutrition and Feeding, Ministry of Agriculture and Rural Affairs Feed Industry Centre China Agricultural University Beijing 100193 P. R. ChinaState Key Laboratory of Microbial Resources Institute of Microbiology Chinese Academy of Sciences Beijing 100101 P. R. ChinaState Key Laboratory of Microbial Resources Institute of Microbiology Chinese Academy of Sciences Beijing 100101 P. R. ChinaState Key Laboratory of Microbial Resources Institute of Microbiology Chinese Academy of Sciences Beijing 100101 P. R. ChinaDepartment of Ophthalmology Peking University Third Hospital Beijing 100191 P. R. ChinaState Key Laboratory of Microbial Resources Institute of Microbiology Chinese Academy of Sciences Beijing 100101 P. R. ChinaAbstract Airborne viruses are ubiquitous and play critical roles in maintaining ecosystem balance, however, they remain unexplored. Here, it is aimed to demonstrate that highly diverse airborne viromes carry out specific metabolic functions and use different transmission modes under different air quality conditions. A total of 263.5‐Gb data are collected from 13 air samples for viral metagenomic analysis. After assembly and curation, a total of 12 484 viral contigs (1.5–184.2 kb) are assigned to 221 genus‐level clades belonging to 47 families, 19 orders, and 15 classes. The composition of viral communities is influenced by weather conditions, with the main biomarker being Caudoviricetes. The most dominant viruses in these air samples belong to the dsDNA Caudoviricetes (54.0%) and ssDNA Repensiviricetes (31.2%) classes. Twelve novel candidate viruses are identified at the order/family/genus levels by alignment of complete genomes and core genes. Notably, Caudoviricetes are highly prevalent in cloudy and smoggy air, whereas Repensiviricetes are highly dominant in sunny and rainy air. Diverse auxiliary metabolic genes of airborne viruses are mainly involved in deoxynucleotide synthesis, implying their unique roles in atmosphere ecosystem. These findings deepen the understanding of the meteorological impacts on viral composition, transmission mode, and ecological roles in the air that we breathe.https://doi.org/10.1002/advs.202404512airborne viromesgenetic diversitymetabolic functionsynoptic variationtransmission mode |
| spellingShingle | Aihua Deng Junyue Wang Lai Li Ruilin Shi Xuemin Li Tingyi Wen Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban Space Advanced Science airborne viromes genetic diversity metabolic function synoptic variation transmission mode |
| title | Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban Space |
| title_full | Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban Space |
| title_fullStr | Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban Space |
| title_full_unstemmed | Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban Space |
| title_short | Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban Space |
| title_sort | synoptic variation drives genetic diversity and transmission mode of airborne dna viruses in urban space |
| topic | airborne viromes genetic diversity metabolic function synoptic variation transmission mode |
| url | https://doi.org/10.1002/advs.202404512 |
| work_keys_str_mv | AT aihuadeng synopticvariationdrivesgeneticdiversityandtransmissionmodeofairbornednavirusesinurbanspace AT junyuewang synopticvariationdrivesgeneticdiversityandtransmissionmodeofairbornednavirusesinurbanspace AT laili synopticvariationdrivesgeneticdiversityandtransmissionmodeofairbornednavirusesinurbanspace AT ruilinshi synopticvariationdrivesgeneticdiversityandtransmissionmodeofairbornednavirusesinurbanspace AT xueminli synopticvariationdrivesgeneticdiversityandtransmissionmodeofairbornednavirusesinurbanspace AT tingyiwen synopticvariationdrivesgeneticdiversityandtransmissionmodeofairbornednavirusesinurbanspace |