Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection

Here, we report the case of an HIV infected patient that was treated for pneumonia with a macrolid antibiotic. The patient experienced a prolongation of the already pathologic QTc interval resulting in repeated torsades de pointes necessitating CPR and implantation of an AICD. This case exemplifies...

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Main Authors: Alexander Shimabukuro-Vornhagen, Jan Rybniker, Shahram Zoghi, Gerd Faetkenheuer, Guido Michels, Erland Erdmann, Michael von Bergwelt-Baildon, Matthias Kochanek
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2010/278427
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author Alexander Shimabukuro-Vornhagen
Jan Rybniker
Shahram Zoghi
Gerd Faetkenheuer
Guido Michels
Erland Erdmann
Michael von Bergwelt-Baildon
Matthias Kochanek
author_facet Alexander Shimabukuro-Vornhagen
Jan Rybniker
Shahram Zoghi
Gerd Faetkenheuer
Guido Michels
Erland Erdmann
Michael von Bergwelt-Baildon
Matthias Kochanek
author_sort Alexander Shimabukuro-Vornhagen
collection DOAJ
description Here, we report the case of an HIV infected patient that was treated for pneumonia with a macrolid antibiotic. The patient experienced a prolongation of the already pathologic QTc interval resulting in repeated torsades de pointes necessitating CPR and implantation of an AICD. This case exemplifies that torsades de pointes due to acquired long QT syndrome is a serious and potentially fatal complication in HIV-positive patients.
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spelling doaj-art-63c587b2bb1b452d855637eda7877b1d2025-02-03T06:05:07ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/278427278427Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV InfectionAlexander Shimabukuro-Vornhagen0Jan Rybniker1Shahram Zoghi2Gerd Faetkenheuer3Guido Michels4Erland Erdmann5Michael von Bergwelt-Baildon6Matthias Kochanek7Department I of Internal Medicine, University Hospital of Cologne, 50937 Cologne, GermanyDepartment I of Internal Medicine, University Hospital of Cologne, 50937 Cologne, GermanyDepartment I of Internal Medicine, University Hospital of Cologne, 50937 Cologne, GermanyDepartment I of Internal Medicine, University Hospital of Cologne, 50937 Cologne, GermanyDepartment III of Internal Medicine, University Hospital of Cologne, 50937 Cologne, GermanyDepartment III of Internal Medicine, University Hospital of Cologne, 50937 Cologne, GermanyDepartment I of Internal Medicine, University Hospital of Cologne, 50937 Cologne, GermanyDepartment I of Internal Medicine, University Hospital of Cologne, 50937 Cologne, GermanyHere, we report the case of an HIV infected patient that was treated for pneumonia with a macrolid antibiotic. The patient experienced a prolongation of the already pathologic QTc interval resulting in repeated torsades de pointes necessitating CPR and implantation of an AICD. This case exemplifies that torsades de pointes due to acquired long QT syndrome is a serious and potentially fatal complication in HIV-positive patients.http://dx.doi.org/10.1155/2010/278427
spellingShingle Alexander Shimabukuro-Vornhagen
Jan Rybniker
Shahram Zoghi
Gerd Faetkenheuer
Guido Michels
Erland Erdmann
Michael von Bergwelt-Baildon
Matthias Kochanek
Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection
Case Reports in Medicine
title Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection
title_full Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection
title_fullStr Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection
title_full_unstemmed Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection
title_short Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection
title_sort acquired long qt syndrome and torsade de pointes associated with hiv infection
url http://dx.doi.org/10.1155/2010/278427
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