The impact of different ovarian stimulation protocols on the expression levels of GDF-9 and BMP-15 in cumulus cells of follicles

The impact of different ovarian stimulation protocols on the expression levels of GDF-9 and BMP-15 in cumulus cells of follicles

ObjectiveTo analyze the expression levels of the oocyte-secreted factors growth differentiation factor-9 (GDF-9) and bone morphogenetic protein-15 (BMP-15) in cumulus cells (CCs) under different controlled ovarian stimulation (COS) protocols and their association with oocyte maturity and embryo deve...

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Bibliographic Details
Main Authors: Lili Cheng, Jie Zhang, Dongxiu Li, Pengyu Xu, Shan Liu, Ruijuan Guo, Xue Wang, Li Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Endocrinology
Subjects:
oocyte-secreted factors
granulosa cells
oocyte maturation
controlled ovarian stimulation
embryo development
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1572388/full
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