Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh
Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is a locally aggressive mesenchymal neoplasm composed either entirely or partly of an adipocytic proliferation showing at least focal nuclear atypia in both adipocytes and stromal cells. ALT most frequently occurs in deep soft tis...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2020/8846932 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832566067067617280 |
|---|---|
| author | Chairat Burusapat Nuttadon Wongprakob Nutthapong Wanichjaroen Chatchai Pruksapong Kantang Satayasoontorn |
| author_facet | Chairat Burusapat Nuttadon Wongprakob Nutthapong Wanichjaroen Chatchai Pruksapong Kantang Satayasoontorn |
| author_sort | Chairat Burusapat |
| collection | DOAJ |
| description | Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is a locally aggressive mesenchymal neoplasm composed either entirely or partly of an adipocytic proliferation showing at least focal nuclear atypia in both adipocytes and stromal cells. ALT most frequently occurs in deep soft tissue of proximal extremities (thigh and buttock) and usually presents as a deep-seated, painless mass that can slowly attain a very large size, which is one of the most common sarcomas of extremity. In the patients who presented with deep-seated tumor, distinction between intramuscular lipoma and well-differentiated liposarcoma is important due to the differences in treatment and prognosis. However, atypical well-differentiated liposarcoma with intramuscular lipoma-like component of the thigh is extremely rare. Moreover, the infiltrative growth pattern or intramuscular component may lead to a misinterpretation as intramuscular lipoma on a small biopsy. We present an unusual case of a female who presented with symptomatic mass at the thigh which has rarely been reported in English literature as an infiltrative intramuscular lipoma-like growth pattern of well-differentiated liposarcoma. Therefore, preoperative diagnosis is necessary, and correlation with imaging studies is required when one encounters with a large deep-seated mass. Atypical lipomatous tumor or well-differentiated liposarcoma should be kept in mind in the patient who presents with abnormal thigh mass. |
| format | Article |
| id | doaj-art-63bebf542d8c42dea8b78c303d7e4b73 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-63bebf542d8c42dea8b78c303d7e4b732025-02-03T01:05:16ZengWileyCase Reports in Surgery2090-69002090-69192020-01-01202010.1155/2020/88469328846932Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the ThighChairat Burusapat0Nuttadon Wongprakob1Nutthapong Wanichjaroen2Chatchai Pruksapong3Kantang Satayasoontorn4Division of Plastic and Reconstructive Surgery, Department of Surgery, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, ThailandDivision of Plastic and Reconstructive Surgery, Department of Surgery, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, ThailandDivision of Plastic and Reconstructive Surgery, Department of Surgery, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, ThailandDivision of Plastic and Reconstructive Surgery, Department of Surgery, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, ThailandDepartment of Pathology and Laboratory Medicine, Phramongkutklao Hospital, Bangkok, ThailandAtypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is a locally aggressive mesenchymal neoplasm composed either entirely or partly of an adipocytic proliferation showing at least focal nuclear atypia in both adipocytes and stromal cells. ALT most frequently occurs in deep soft tissue of proximal extremities (thigh and buttock) and usually presents as a deep-seated, painless mass that can slowly attain a very large size, which is one of the most common sarcomas of extremity. In the patients who presented with deep-seated tumor, distinction between intramuscular lipoma and well-differentiated liposarcoma is important due to the differences in treatment and prognosis. However, atypical well-differentiated liposarcoma with intramuscular lipoma-like component of the thigh is extremely rare. Moreover, the infiltrative growth pattern or intramuscular component may lead to a misinterpretation as intramuscular lipoma on a small biopsy. We present an unusual case of a female who presented with symptomatic mass at the thigh which has rarely been reported in English literature as an infiltrative intramuscular lipoma-like growth pattern of well-differentiated liposarcoma. Therefore, preoperative diagnosis is necessary, and correlation with imaging studies is required when one encounters with a large deep-seated mass. Atypical lipomatous tumor or well-differentiated liposarcoma should be kept in mind in the patient who presents with abnormal thigh mass.http://dx.doi.org/10.1155/2020/8846932 |
| spellingShingle | Chairat Burusapat Nuttadon Wongprakob Nutthapong Wanichjaroen Chatchai Pruksapong Kantang Satayasoontorn Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh Case Reports in Surgery |
| title | Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh |
| title_full | Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh |
| title_fullStr | Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh |
| title_full_unstemmed | Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh |
| title_short | Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh |
| title_sort | atypical lipomatous tumor well differentiated liposarcoma with intramuscular lipoma like component of the thigh |
| url | http://dx.doi.org/10.1155/2020/8846932 |
| work_keys_str_mv | AT chairatburusapat atypicallipomatoustumorwelldifferentiatedliposarcomawithintramuscularlipomalikecomponentofthethigh AT nuttadonwongprakob atypicallipomatoustumorwelldifferentiatedliposarcomawithintramuscularlipomalikecomponentofthethigh AT nutthapongwanichjaroen atypicallipomatoustumorwelldifferentiatedliposarcomawithintramuscularlipomalikecomponentofthethigh AT chatchaipruksapong atypicallipomatoustumorwelldifferentiatedliposarcomawithintramuscularlipomalikecomponentofthethigh AT kantangsatayasoontorn atypicallipomatoustumorwelldifferentiatedliposarcomawithintramuscularlipomalikecomponentofthethigh |