Pituitary androgen receptor signalling regulates prolactin but not gonadotrophins in the male mouse.

Production of the androgen testosterone is controlled by a negative feedback loop within the hypothalamic-pituitary-gonadal (HPG) axis. Stimulation of testicular Leydig cells by pituitary luteinising hormone (LH) is under the control of hypothalamic gonadotrophin releasing hormone (GnRH), while supp...

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Bibliographic Details
Main Authors: Laura O'Hara, Michael Curley, Maria Tedim Ferreira, Lyndsey Cruickshanks, Laura Milne, Lee B Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0121657
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