Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection
A 13-month-old male presented with repetitive episodes of myoclonic jerks of the head and extremities for two months. His past medical history revealed that his non-immunized mother had measles at the time of delivery. Measles antibody titers in serum and cerebrospinal fluid (CSF) were 1/512...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2005-01-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/2683 |
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| _version_ | 1850236508304310272 |
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| author | Enver Simşek Ayhan Oztürk Cevdet Yavuz Kenan Kocabay |
| author_facet | Enver Simşek Ayhan Oztürk Cevdet Yavuz Kenan Kocabay |
| author_sort | Enver Simşek |
| collection | DOAJ |
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A 13-month-old male presented with repetitive episodes of myoclonic jerks of the head and extremities for two months. His past medical history revealed that his non-immunized mother had measles at the time of delivery. Measles antibody titers in serum and cerebrospinal fluid (CSF) were 1/512 (hemagglutinin inhibition [HI]) and 1/128 HI, respectively. Immunofixation electrophoresis of CSF revealed an oligoclonal IgG band. The magnetic resonance imaging (MRI) of the brain on T2-weighted images showed lesions of high signal intensity in the subcortical white matter. Electroencephalography (EEG) revealed periodic high-amplitude slow waves. Diagnosis of subacute sclerosing panencephalitis (SSPE) was based upon clinical presentation, a characteristic EEG, and abnormal CSF studies. MRI findings supported the diagnosis. To the best of our knowledge, this is only the 3rd case to date, of SSPE-associated congenital measles in the literature.
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| format | Article |
| id | doaj-art-63a6afd02bf54ed199f9f1822b2e4096 |
| institution | OA Journals |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2005-01-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-63a6afd02bf54ed199f9f1822b2e40962025-08-20T02:01:57ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212005-01-01471Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infectionEnver Simşek0Ayhan OztürkCevdet YavuzKenan KocabayDepartment of Pediatrics, Abant Izzet Baysal University, Düzce Faculty of Medicine, Düzce, Turkey. A 13-month-old male presented with repetitive episodes of myoclonic jerks of the head and extremities for two months. His past medical history revealed that his non-immunized mother had measles at the time of delivery. Measles antibody titers in serum and cerebrospinal fluid (CSF) were 1/512 (hemagglutinin inhibition [HI]) and 1/128 HI, respectively. Immunofixation electrophoresis of CSF revealed an oligoclonal IgG band. The magnetic resonance imaging (MRI) of the brain on T2-weighted images showed lesions of high signal intensity in the subcortical white matter. Electroencephalography (EEG) revealed periodic high-amplitude slow waves. Diagnosis of subacute sclerosing panencephalitis (SSPE) was based upon clinical presentation, a characteristic EEG, and abnormal CSF studies. MRI findings supported the diagnosis. To the best of our knowledge, this is only the 3rd case to date, of SSPE-associated congenital measles in the literature. https://turkjpediatr.org/article/view/2683 |
| spellingShingle | Enver Simşek Ayhan Oztürk Cevdet Yavuz Kenan Kocabay Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection The Turkish Journal of Pediatrics |
| title | Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection |
| title_full | Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection |
| title_fullStr | Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection |
| title_full_unstemmed | Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection |
| title_short | Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection |
| title_sort | subacute sclerosing panencephalitis sspe associated with congenital measles infection |
| url | https://turkjpediatr.org/article/view/2683 |
| work_keys_str_mv | AT enversimsek subacutesclerosingpanencephalitissspeassociatedwithcongenitalmeaslesinfection AT ayhanozturk subacutesclerosingpanencephalitissspeassociatedwithcongenitalmeaslesinfection AT cevdetyavuz subacutesclerosingpanencephalitissspeassociatedwithcongenitalmeaslesinfection AT kenankocabay subacutesclerosingpanencephalitissspeassociatedwithcongenitalmeaslesinfection |