Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series

Introduction: Buprenorphine is used for treating opioid use disorder, but its role as an analgesic in the emergency department (ED) is frequently overlooked. Emerging evidence indicates that, at low doses, it can be used safely and advantageously as an alternative to full-agonist opioids for treatin...

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Main Authors: Jonathan Lee, Nicholas Ashenburg, Joshua Park, Terence Ahern
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2025-07-01
Series:Clinical Practice and Cases in Emergency Medicine
Online Access:https://escholarship.org/uc/item/3x35f05c
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author Jonathan Lee
Nicholas Ashenburg
Joshua Park
Terence Ahern
author_facet Jonathan Lee
Nicholas Ashenburg
Joshua Park
Terence Ahern
author_sort Jonathan Lee
collection DOAJ
description Introduction: Buprenorphine is used for treating opioid use disorder, but its role as an analgesic in the emergency department (ED) is frequently overlooked. Emerging evidence indicates that, at low doses, it can be used safely and advantageously as an alternative to full-agonist opioids for treating acute pain. Case Series: This case series examines the novel use of intravenous (IV) low-dose buprenorphine for acute pain management in the ED for five patients presenting with diverse past medical history and varied painful indications. Conclusion: Intravenous low-dose buprenorphine may represent an important new tool in our ED armamentarium, and research into its role in emergency pain management is warranted. Further work is needed to determine optimal dosing strategies and identify which patients will be most likely to benefit from IV low-dosebuprenorphine in the ED.
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institution Kabale University
issn 2474-252X
language English
publishDate 2025-07-01
publisher eScholarship Publishing, University of California
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series Clinical Practice and Cases in Emergency Medicine
spelling doaj-art-63a4ef55097644c1af4be0713e1a4e0b2025-08-20T03:41:52ZengeScholarship Publishing, University of CaliforniaClinical Practice and Cases in Emergency Medicine2474-252X2025-07-019326426710.5811/cpcem.43494cpcem-9-264Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case SeriesJonathan Lee0Nicholas Ashenburg1Joshua Park2Terence Ahern3Stanford University School of Medicine, Department of Anesthesiology, Perioperative, and Pain Medicine, Palo Alto, CaliforniaStanford University School of Medicine, Department of Emergency Medicine, Palo Alto, CaliforniaStanford Health Care, Department of Pharmacy, Palo Alto, CaliforniaStanford University School of Medicine, Department of Emergency Medicine, Palo Alto, CaliforniaIntroduction: Buprenorphine is used for treating opioid use disorder, but its role as an analgesic in the emergency department (ED) is frequently overlooked. Emerging evidence indicates that, at low doses, it can be used safely and advantageously as an alternative to full-agonist opioids for treating acute pain. Case Series: This case series examines the novel use of intravenous (IV) low-dose buprenorphine for acute pain management in the ED for five patients presenting with diverse past medical history and varied painful indications. Conclusion: Intravenous low-dose buprenorphine may represent an important new tool in our ED armamentarium, and research into its role in emergency pain management is warranted. Further work is needed to determine optimal dosing strategies and identify which patients will be most likely to benefit from IV low-dosebuprenorphine in the ED.https://escholarship.org/uc/item/3x35f05c
spellingShingle Jonathan Lee
Nicholas Ashenburg
Joshua Park
Terence Ahern
Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series
Clinical Practice and Cases in Emergency Medicine
title Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series
title_full Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series
title_fullStr Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series
title_full_unstemmed Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series
title_short Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series
title_sort intravenous low dose buprenorphine for acute pain management in the emergency department a case series
url https://escholarship.org/uc/item/3x35f05c
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