SNAKE VENOMS AND THEIR THERAPEUTIC POTENTIAL
Snake venoms are complex heterogeneous mixtures containing different bioactive molecules with multivalent nature. Most of these components are proteins displaying enzymatic or non-enzymatic biological and pharmacological activities and toxicological potential. Their funct...
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| Format: | Article |
| Language: | English |
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Trakia University
2024-09-01
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| Series: | Trakia Journal of Sciences |
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| Online Access: | https://tjs.trakia-uni.bg/index.php/tjs/article/view/46/49 |
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| author | Y.Petseva K.Mladenova J.Doumanov S.Petrova |
| author_facet | Y.Petseva K.Mladenova J.Doumanov S.Petrova |
| author_sort | Y.Petseva |
| collection | DOAJ |
| description | Snake venoms are complex heterogeneous mixtures containing different bioactive molecules with multivalent nature. Most of these components are proteins displaying enzymatic or non-enzymatic biological and pharmacological activities and toxicological potential. Their functional activities on various tissues and organs lead to the manifestation of diverse effects such as neurotoxicity, myotoxicity, cytotoxicity, inflammation, influence on hemostasis, apoptosis, necrosis and other, causing simultaneous damage to various physiological systems. At the same time, the unique molecular features of snake venom compounds make them valuable scientific tools for understanding different physiological processes, and allows them to fulfil their great potential in medicine and pharmacology as therapeutic agents and diagnostic tools. Many snake venom toxins have been found to exert analgesic, antiplatelet, hypotensive,antitumor, anti/pro-inflammatory or other potencies, as some of them have already been used as a base for design of commercially available pharmaceuticals. |
| format | Article |
| id | doaj-art-63a14363e9af4d3d8e8b769e73368a4b |
| institution | OA Journals |
| issn | 1313-3551 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Trakia University |
| record_format | Article |
| series | Trakia Journal of Sciences |
| spelling | doaj-art-63a14363e9af4d3d8e8b769e73368a4b2025-08-20T01:51:32ZengTrakia UniversityTrakia Journal of Sciences1313-35512024-09-0122325226010.15547/tjs.2024.03.009SNAKE VENOMS AND THEIR THERAPEUTIC POTENTIALY.PetsevaK.MladenovaJ.DoumanovS.PetrovaSnake venoms are complex heterogeneous mixtures containing different bioactive molecules with multivalent nature. Most of these components are proteins displaying enzymatic or non-enzymatic biological and pharmacological activities and toxicological potential. Their functional activities on various tissues and organs lead to the manifestation of diverse effects such as neurotoxicity, myotoxicity, cytotoxicity, inflammation, influence on hemostasis, apoptosis, necrosis and other, causing simultaneous damage to various physiological systems. At the same time, the unique molecular features of snake venom compounds make them valuable scientific tools for understanding different physiological processes, and allows them to fulfil their great potential in medicine and pharmacology as therapeutic agents and diagnostic tools. Many snake venom toxins have been found to exert analgesic, antiplatelet, hypotensive,antitumor, anti/pro-inflammatory or other potencies, as some of them have already been used as a base for design of commercially available pharmaceuticals.https://tjs.trakia-uni.bg/index.php/tjs/article/view/46/49snake venomsenzymesneurotoxinstherapeutic applicationsdrugs |
| spellingShingle | Y.Petseva K.Mladenova J.Doumanov S.Petrova SNAKE VENOMS AND THEIR THERAPEUTIC POTENTIAL Trakia Journal of Sciences snake venoms enzymes neurotoxins therapeutic applications drugs |
| title | SNAKE VENOMS AND THEIR THERAPEUTIC POTENTIAL |
| title_full | SNAKE VENOMS AND THEIR THERAPEUTIC POTENTIAL |
| title_fullStr | SNAKE VENOMS AND THEIR THERAPEUTIC POTENTIAL |
| title_full_unstemmed | SNAKE VENOMS AND THEIR THERAPEUTIC POTENTIAL |
| title_short | SNAKE VENOMS AND THEIR THERAPEUTIC POTENTIAL |
| title_sort | snake venoms and their therapeutic potential |
| topic | snake venoms enzymes neurotoxins therapeutic applications drugs |
| url | https://tjs.trakia-uni.bg/index.php/tjs/article/view/46/49 |
| work_keys_str_mv | AT ypetseva snakevenomsandtheirtherapeuticpotential AT kmladenova snakevenomsandtheirtherapeuticpotential AT jdoumanov snakevenomsandtheirtherapeuticpotential AT spetrova snakevenomsandtheirtherapeuticpotential |