Utility of tryptase genotyping in the screening, diagnosis, and management of systemic mastocytosis

Utility of tryptase genotyping in the screening, diagnosis, and management of systemic mastocytosis

Tryptase genotyping has an expanding role in the screening, diagnosis, and management of patients with systemic mastocytosis (SM). Reference ranges for basal serum tryptase (BST) based on increased TPSAB1 gene copy number can guide whether a patient's BST value is normal according to their spec...

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Bibliographic Details
Main Authors:	Jeremy C. McMurray, Brandon J. Schornack, Joaquin Villar, Tracy I. George, Nathan A. Boggs
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Allergy
Subjects:	systemic mastocytosis (SM) tryptase genotyping basal serum tryptase (BST) hereditary alpha tryptasemia tyrosine kinase inhibitors (TKIs)
Online Access:	https://www.frontiersin.org/articles/10.3389/falgy.2025.1599358/full
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