Epidemiology and survival analysis of head and neck cancer: Results from comprehensive care center in North India
Background: In India Head and Neck Cancers (HNCs) are the most common cancer among men and rank 2nd overall. There is wide variation in the incidence and anatomic distribution of HNCs in India compared to western countries. This variation is mostly due to demographic differences in cigarette and alc...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
|
| Series: | Oral Oncology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906023000122 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Background: In India Head and Neck Cancers (HNCs) are the most common cancer among men and rank 2nd overall. There is wide variation in the incidence and anatomic distribution of HNCs in India compared to western countries. This variation is mostly due to demographic differences in cigarette and alcohol consumption behaviours, which led to the development of over 80% of all HNCs diagnosed worldwide. The purpose of this study was to understand the epidemiology of HNCs in terms of demographic and clinical characteristics at the time of diagnosis and their survival. Methods: This was a retrospective single-center hospital based cancer registry study which included all primary diagnosed HNCs cases attending various departments of our hospital between January 1, 2016–December 31, 2020. Patients’ socio-demographic characteristics, clinic-pathological details like the stage of cancer, treatment received and follow up details were extracted from medical records. Survival was estimated by the Kaplan Meier method and compared by the log-rank test. Results: A total of 574 confirmed cases of HNCs were include in this study. Majority of the patients presented in advanced stage. The treatment intent was curative in 80% and palliative for 20%. The median follow up period was 20.0 months. After 18 months of follow up 58.5% of the cases survived. There was no statistical significant difference in survival between men and women and patients aged below and above 60 years. Advanced stage at presentation, grade III histological differentiation, presence of lymphovascular invasion, nodal stage specially N2/N3 and palliative treatment were associated with poor outcomes. Conclusion: This study reports the demographic profile and pattern of care of patients with HNCs from a comprehensive care center in North India. |
|---|---|
| ISSN: | 2772-9060 |