Comparison of Biparametric and Multiparametric Prostate Magnetic Resonance Imaging in Predicting Oncologic Outcomes After Radical Prostatectomy
Objective: This study aimed to evaluate the difference in predicting the pathological stage of retropubic radical prostatectomy (RRP) and biochemical recurrence (BCR) in patients with Prostate Imaging Reporting and Data System (PIRADS) scores of 3 and 4 on biparametric prostate magnetic resonance im...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2022-12-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-78785 |
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| author | Ozgur EFILOGLU Nesrin GUNDUZ Ayberk IPLIKCI Mahmut Bilal DOGAN Mehmet Caglar CAKICI Turgay TURAN Asif YILDIRIM |
| author_facet | Ozgur EFILOGLU Nesrin GUNDUZ Ayberk IPLIKCI Mahmut Bilal DOGAN Mehmet Caglar CAKICI Turgay TURAN Asif YILDIRIM |
| author_sort | Ozgur EFILOGLU |
| collection | DOAJ |
| description | Objective: This study aimed to evaluate the difference in predicting the pathological stage of retropubic radical prostatectomy (RRP) and biochemical recurrence (BCR) in patients with Prostate Imaging Reporting and Data System (PIRADS) scores of 3 and 4 on biparametric prostate magnetic resonance imaging (bpMRI) compared to patients who upgraded from PIRADS 3 to PIRADS 4 based on the contrast-enhanced PIRADS version 2.1.
Methods: This study evaluated 107 patients who underwent RRP and had preoperative multiparametric prostate magnetic resonance imaging (mpMRI) and were followed regularly. Group 1 included 31 patients evaluated as PIRADS 3 in both bpMRI and mpMRI, group 2 included 31 patients evaluated as PIRADS 3 in bpMRI and PIRADS 4 in mpMRI, and group 3 included 45 patients evaluated as PIRADS 4 without contrast. Comparisons were made between groups 1 and 2 and between groups 2 and 3.
Results: No significant difference was found between the groups in terms of demographic data, preoperative or postoperative radiology, and pathology findings. Extraprostatic extension positivity and BCR were more common in group 2 compared to group 1 although not significant. Multivariate regression analysis was performed to determine the risk factors in predicting BCR, which revealed the positivity of seminal vesicle invasion and high pathological stage in the pathology report as significant factors. Prostate-specific antigen (PSA) and PSA density were higher in group 3 than in group 2, but without significance.
Conclusions: This study revealed that mpMRI did not contribute in predicting BCR after RRP compared to bpMRI. |
| format | Article |
| id | doaj-art-6391db9938874e04afbd034f5e7fafd3 |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-6391db9938874e04afbd034f5e7fafd32025-01-30T07:07:34ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062022-12-0137431331910.4274/MMJ.galenos.2022.78785MEDJ-78785Comparison of Biparametric and Multiparametric Prostate Magnetic Resonance Imaging in Predicting Oncologic Outcomes After Radical ProstatectomyOzgur EFILOGLU0Nesrin GUNDUZ1Ayberk IPLIKCI2Mahmut Bilal DOGAN3Mehmet Caglar CAKICI4Turgay TURAN5Asif YILDIRIM6Istanbul Medeniyet University Faculty of Medicine, Department of Urology, Istanbul, TurkeyIstanbul Medeniyet University Faculty of Medicine, Department of Radiology, Istanbul, TurkeyIstanbul Medeniyet University Faculty of Medicine, Department of Urology, Istanbul, TurkeyIstanbul Medeniyet University Faculty of Medicine, Department of Radiology, Istanbul, TurkeyIstanbul Medeniyet University Faculty of Medicine, Department of Urology, Istanbul, TurkeyIstanbul Medeniyet University Faculty of Medicine, Department of Urology, Istanbul, TurkeyIstanbul Medeniyet University Faculty of Medicine, Department of Urology, Istanbul, TurkeyObjective: This study aimed to evaluate the difference in predicting the pathological stage of retropubic radical prostatectomy (RRP) and biochemical recurrence (BCR) in patients with Prostate Imaging Reporting and Data System (PIRADS) scores of 3 and 4 on biparametric prostate magnetic resonance imaging (bpMRI) compared to patients who upgraded from PIRADS 3 to PIRADS 4 based on the contrast-enhanced PIRADS version 2.1. Methods: This study evaluated 107 patients who underwent RRP and had preoperative multiparametric prostate magnetic resonance imaging (mpMRI) and were followed regularly. Group 1 included 31 patients evaluated as PIRADS 3 in both bpMRI and mpMRI, group 2 included 31 patients evaluated as PIRADS 3 in bpMRI and PIRADS 4 in mpMRI, and group 3 included 45 patients evaluated as PIRADS 4 without contrast. Comparisons were made between groups 1 and 2 and between groups 2 and 3. Results: No significant difference was found between the groups in terms of demographic data, preoperative or postoperative radiology, and pathology findings. Extraprostatic extension positivity and BCR were more common in group 2 compared to group 1 although not significant. Multivariate regression analysis was performed to determine the risk factors in predicting BCR, which revealed the positivity of seminal vesicle invasion and high pathological stage in the pathology report as significant factors. Prostate-specific antigen (PSA) and PSA density were higher in group 3 than in group 2, but without significance. Conclusions: This study revealed that mpMRI did not contribute in predicting BCR after RRP compared to bpMRI.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-78785cancerprostate magnetic resonance imagingradical prostatectomy |
| spellingShingle | Ozgur EFILOGLU Nesrin GUNDUZ Ayberk IPLIKCI Mahmut Bilal DOGAN Mehmet Caglar CAKICI Turgay TURAN Asif YILDIRIM Comparison of Biparametric and Multiparametric Prostate Magnetic Resonance Imaging in Predicting Oncologic Outcomes After Radical Prostatectomy Medeniyet Medical Journal cancer prostate magnetic resonance imaging radical prostatectomy |
| title | Comparison of Biparametric and Multiparametric Prostate Magnetic Resonance Imaging in Predicting Oncologic Outcomes After Radical Prostatectomy |
| title_full | Comparison of Biparametric and Multiparametric Prostate Magnetic Resonance Imaging in Predicting Oncologic Outcomes After Radical Prostatectomy |
| title_fullStr | Comparison of Biparametric and Multiparametric Prostate Magnetic Resonance Imaging in Predicting Oncologic Outcomes After Radical Prostatectomy |
| title_full_unstemmed | Comparison of Biparametric and Multiparametric Prostate Magnetic Resonance Imaging in Predicting Oncologic Outcomes After Radical Prostatectomy |
| title_short | Comparison of Biparametric and Multiparametric Prostate Magnetic Resonance Imaging in Predicting Oncologic Outcomes After Radical Prostatectomy |
| title_sort | comparison of biparametric and multiparametric prostate magnetic resonance imaging in predicting oncologic outcomes after radical prostatectomy |
| topic | cancer prostate magnetic resonance imaging radical prostatectomy |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-78785 |
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