Biomarker profile of a Chinese ALS cohort: A comprehensive clinical-biomarkers-imaging analysis

Biomarker profile of a Chinese ALS cohort: A comprehensive clinical-biomarkers-imaging analysis

Background: Amyotrophic lateral sclerosis (ALS) is a fatal central nervous system neurodegenerative disease, but the relationships among genetic mutations, plasma biomarkers, glymphatic system and clinical variables remain unclear. Methods: This study retrospectively collected data from April 2015 t...

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Main Authors: Youliang Wang, Jie Lin, Yongqiang Qu, Ying Ding, Zhixian Ye, Zhibao Zhu, Wei Chen, Zhili Chen, Huamei Sun, Fangwei Hu, Chaohan Chen, Ling Fang, Rui Li, Bo Zhang, Ning Wang, Ying Fu, Wanjin Chen, Qijie Zhang
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Neurobiology of Disease
Subjects:
Amyotrophic lateral sclerosis
Genetic ALS
Protein aggregation
Astrocyte
Biomarker
Glymphatic system
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612500275X
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