Targeting T cells with tetravalent bispecific antibodies for the treatment of graft-versus-host disease

Targeting T cells with tetravalent bispecific antibodies for the treatment of graft-versus-host disease

Abstract: Allogeneic hematopoietic stem cell transplantation is an established treatment for hematological malignancies and some genetic diseases. Acute graft-versus-host disease (GVHD) is the most common and debilitating side effect with poor survival rates of 5% to 30% for severe cases. In this ma...

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Bibliographic Details
Main Authors: Madelyn Espinosa-Cotton, Sayed Shahabuddin Hoseini, Ileana C. Miranda, John Herrick, Nai-Kong V. Cheung
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952924005561
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