A Preliminary Study on Transcriptional Regulation of SNP Site C-1888T in the Promoter Region of Human PLUNC Gene and Nasopharyngeal Carcinoma Susceptibility

Conclusion: The transcription factors XFD3 and EVI1 may be involved in the transcriptional regulation of PLUNC gene, and EVI1 can bind to the promoter region of PLUNC gene in SUNE1 NPC cells, thus associated with the susceptibility/risk of NPC.

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Main Authors: Beina Liu, Rong Wang, Ying He
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Genetics Research
Online Access:http://dx.doi.org/10.1155/genr/5148918
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author Beina Liu
Rong Wang
Ying He
author_facet Beina Liu
Rong Wang
Ying He
author_sort Beina Liu
collection DOAJ
description Conclusion: The transcription factors XFD3 and EVI1 may be involved in the transcriptional regulation of PLUNC gene, and EVI1 can bind to the promoter region of PLUNC gene in SUNE1 NPC cells, thus associated with the susceptibility/risk of NPC.
format Article
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institution DOAJ
issn 1469-5073
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series Genetics Research
spelling doaj-art-635ee0ee2e3a4601a463c19cd70579982025-08-20T02:40:40ZengWileyGenetics Research1469-50732024-01-01202410.1155/genr/5148918A Preliminary Study on Transcriptional Regulation of SNP Site C-1888T in the Promoter Region of Human PLUNC Gene and Nasopharyngeal Carcinoma SusceptibilityBeina Liu0Rong Wang1Ying He2Department of Otolaryngology-Head and Neck SurgeryDepartment of Otolaryngology-Head and Neck SurgeryDepartment of Otolaryngology-Head and Neck SurgeryConclusion: The transcription factors XFD3 and EVI1 may be involved in the transcriptional regulation of PLUNC gene, and EVI1 can bind to the promoter region of PLUNC gene in SUNE1 NPC cells, thus associated with the susceptibility/risk of NPC.http://dx.doi.org/10.1155/genr/5148918
spellingShingle Beina Liu
Rong Wang
Ying He
A Preliminary Study on Transcriptional Regulation of SNP Site C-1888T in the Promoter Region of Human PLUNC Gene and Nasopharyngeal Carcinoma Susceptibility
Genetics Research
title A Preliminary Study on Transcriptional Regulation of SNP Site C-1888T in the Promoter Region of Human PLUNC Gene and Nasopharyngeal Carcinoma Susceptibility
title_full A Preliminary Study on Transcriptional Regulation of SNP Site C-1888T in the Promoter Region of Human PLUNC Gene and Nasopharyngeal Carcinoma Susceptibility
title_fullStr A Preliminary Study on Transcriptional Regulation of SNP Site C-1888T in the Promoter Region of Human PLUNC Gene and Nasopharyngeal Carcinoma Susceptibility
title_full_unstemmed A Preliminary Study on Transcriptional Regulation of SNP Site C-1888T in the Promoter Region of Human PLUNC Gene and Nasopharyngeal Carcinoma Susceptibility
title_short A Preliminary Study on Transcriptional Regulation of SNP Site C-1888T in the Promoter Region of Human PLUNC Gene and Nasopharyngeal Carcinoma Susceptibility
title_sort preliminary study on transcriptional regulation of snp site c 1888t in the promoter region of human plunc gene and nasopharyngeal carcinoma susceptibility
url http://dx.doi.org/10.1155/genr/5148918
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