Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature

Subcorneal pustular dermatosis (SCPD, also known as Sneddon-Wilkinson disease) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence. The primary lesions are pea-sized pustules classically described...

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Main Authors: Massimiliano Scalvenzi, Franco Palmisano, Maria Carmela Annunziata, Ernesto Mezza, Immacolata Cozzolino, Claudia Costa
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2013/424797
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author Massimiliano Scalvenzi
Franco Palmisano
Maria Carmela Annunziata
Ernesto Mezza
Immacolata Cozzolino
Claudia Costa
author_facet Massimiliano Scalvenzi
Franco Palmisano
Maria Carmela Annunziata
Ernesto Mezza
Immacolata Cozzolino
Claudia Costa
author_sort Massimiliano Scalvenzi
collection DOAJ
description Subcorneal pustular dermatosis (SCPD, also known as Sneddon-Wilkinson disease) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence. The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis, although acantholysis may be reported in older lesions. In this paper we present the case of a 7-year-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Dapsone has been successfully used in the treatment of the disease.
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series Case Reports in Dermatological Medicine
spelling doaj-art-63502e79b8f341168e30d06b4110fdfc2025-02-03T01:09:34ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712013-01-01201310.1155/2013/424797424797Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the LiteratureMassimiliano Scalvenzi0Franco Palmisano1Maria Carmela Annunziata2Ernesto Mezza3Immacolata Cozzolino4Claudia Costa5Department of Dermatology, Federico II University, Via Pansini 5, 80131 Naples, ItalyDepartment of Dermatology, Federico II University, Via Pansini 5, 80131 Naples, ItalyDepartment of Dermatology, Federico II University, Via Pansini 5, 80131 Naples, ItalyDepartment of Biomorphological and Functional Sciences, Federico II University, 80131 Naples, ItalyDepartment of Biomorphological and Functional Sciences, Federico II University, 80131 Naples, ItalyDepartment of Dermatology, Federico II University, Via Pansini 5, 80131 Naples, ItalySubcorneal pustular dermatosis (SCPD, also known as Sneddon-Wilkinson disease) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence. The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis, although acantholysis may be reported in older lesions. In this paper we present the case of a 7-year-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Dapsone has been successfully used in the treatment of the disease.http://dx.doi.org/10.1155/2013/424797
spellingShingle Massimiliano Scalvenzi
Franco Palmisano
Maria Carmela Annunziata
Ernesto Mezza
Immacolata Cozzolino
Claudia Costa
Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature
Case Reports in Dermatological Medicine
title Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature
title_full Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature
title_fullStr Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature
title_full_unstemmed Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature
title_short Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature
title_sort subcorneal pustular dermatosis in childhood a case report and review of the literature
url http://dx.doi.org/10.1155/2013/424797
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