“Mechanics hand” as vaccine related adverse event after COVID-19 vaccination
Autoimmune diseases are now well reported with COVID-19 vaccination. Rheumatological, neurological, cardiac and hematological adverse events are observed globally. Dermatological adverse events are reported in few cases but dermatological with rheumatological manifestation with reversible autoimmune...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Muller Journal of Medical Sciences and Research |
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| Online Access: | https://journals.lww.com/10.4103/mjmsr.mjmsr_35_24 |
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| author | Priyanka Malhotra Mahesh Unni Shital Patil |
| author_facet | Priyanka Malhotra Mahesh Unni Shital Patil |
| author_sort | Priyanka Malhotra |
| collection | DOAJ |
| description | Autoimmune diseases are now well reported with COVID-19 vaccination. Rheumatological, neurological, cardiac and hematological adverse events are observed globally. Dermatological adverse events are reported in few cases but dermatological with rheumatological manifestation with reversible autoimmune phenomenon after COVID-19 vaccination is not reported commonly in literature. “Mechanics hands” is blackish discoloration of palmar aspects of both hands and knuckles commonly reported in rheumatological autoimmune condition such as dermatomyositis. In this case report, 28-year male, presented with polyarthralgia with myalgia and fatigability after 1 month of COVID-19 vaccination. His joint pain symptoms worsened over 4 weeks and developed blackish pigmentation of both hands predominantly involving palms to present as mechanics hands. Vasculitis works up was inconclusive and rheumatologic workup documented raised antinuclear antibody (ANA) titers and rheumatoid factor. We have started him on steroid and hydroxychloroquine and observed satisfactory clinical response with near complete resolution of “mechanics hands” in 24 weeks. Mechanics hands with rheumatological syndrome which is a rare vaccine related adverse event (VRAE), reversible and easily treatable with routinely available medicines and importantly it is having excellent prognosis. Mechanics hand is first time reported in medical literature after COVID-19 vaccination. Minimal systemic VRAEs are known to occur with all viral vector vaccines, but its occurrence is rare and it should not impact on routine vaccinations; as vaccination is a key step in this pandemic to protect mankind. |
| format | Article |
| id | doaj-art-633a0e96778f458f8ea4de061dc6f6a8 |
| institution | DOAJ |
| issn | 0975-9727 2321-3701 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Muller Journal of Medical Sciences and Research |
| spelling | doaj-art-633a0e96778f458f8ea4de061dc6f6a82025-08-20T02:39:16ZengWolters Kluwer Medknow PublicationsMuller Journal of Medical Sciences and Research0975-97272321-37012024-12-0115214515010.4103/mjmsr.mjmsr_35_24“Mechanics hand” as vaccine related adverse event after COVID-19 vaccinationPriyanka MalhotraMahesh UnniShital PatilAutoimmune diseases are now well reported with COVID-19 vaccination. Rheumatological, neurological, cardiac and hematological adverse events are observed globally. Dermatological adverse events are reported in few cases but dermatological with rheumatological manifestation with reversible autoimmune phenomenon after COVID-19 vaccination is not reported commonly in literature. “Mechanics hands” is blackish discoloration of palmar aspects of both hands and knuckles commonly reported in rheumatological autoimmune condition such as dermatomyositis. In this case report, 28-year male, presented with polyarthralgia with myalgia and fatigability after 1 month of COVID-19 vaccination. His joint pain symptoms worsened over 4 weeks and developed blackish pigmentation of both hands predominantly involving palms to present as mechanics hands. Vasculitis works up was inconclusive and rheumatologic workup documented raised antinuclear antibody (ANA) titers and rheumatoid factor. We have started him on steroid and hydroxychloroquine and observed satisfactory clinical response with near complete resolution of “mechanics hands” in 24 weeks. Mechanics hands with rheumatological syndrome which is a rare vaccine related adverse event (VRAE), reversible and easily treatable with routinely available medicines and importantly it is having excellent prognosis. Mechanics hand is first time reported in medical literature after COVID-19 vaccination. Minimal systemic VRAEs are known to occur with all viral vector vaccines, but its occurrence is rare and it should not impact on routine vaccinations; as vaccination is a key step in this pandemic to protect mankind.https://journals.lww.com/10.4103/mjmsr.mjmsr_35_24antinuclear antibody testcovid-19 vaccinemechanics handrheumatological syndromevaccine related adverse event |
| spellingShingle | Priyanka Malhotra Mahesh Unni Shital Patil “Mechanics hand” as vaccine related adverse event after COVID-19 vaccination Muller Journal of Medical Sciences and Research antinuclear antibody test covid-19 vaccine mechanics hand rheumatological syndrome vaccine related adverse event |
| title | “Mechanics hand” as vaccine related adverse event after COVID-19 vaccination |
| title_full | “Mechanics hand” as vaccine related adverse event after COVID-19 vaccination |
| title_fullStr | “Mechanics hand” as vaccine related adverse event after COVID-19 vaccination |
| title_full_unstemmed | “Mechanics hand” as vaccine related adverse event after COVID-19 vaccination |
| title_short | “Mechanics hand” as vaccine related adverse event after COVID-19 vaccination |
| title_sort | mechanics hand as vaccine related adverse event after covid 19 vaccination |
| topic | antinuclear antibody test covid-19 vaccine mechanics hand rheumatological syndrome vaccine related adverse event |
| url | https://journals.lww.com/10.4103/mjmsr.mjmsr_35_24 |
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