Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone Augmentation
Background: Guided bone regeneration (GBR) is a widely used technique in oral and maxillofacial surgery to restore lost bone. The aim of this study is to evaluate the effectiveness of titanium occlusive barriers in GBR for increasing bone volume in both vertical and horizontal dimensions. Methods: A...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-03-01
|
| Series: | Biomimetics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2313-7673/10/3/165 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849342505414295552 |
|---|---|
| author | Luis Leiva-Gea Paulino Sánchez-Palomino Alfonso Lendínez-Jurado María Daniela Corte-Torres Isabel Leiva-Gea Antonio Leiva-Gea |
| author_facet | Luis Leiva-Gea Paulino Sánchez-Palomino Alfonso Lendínez-Jurado María Daniela Corte-Torres Isabel Leiva-Gea Antonio Leiva-Gea |
| author_sort | Luis Leiva-Gea |
| collection | DOAJ |
| description | Background: Guided bone regeneration (GBR) is a widely used technique in oral and maxillofacial surgery to restore lost bone. The aim of this study is to evaluate the effectiveness of titanium occlusive barriers in GBR for increasing bone volume in both vertical and horizontal dimensions. Methods: A prospective analysis was conducted on 11 patients (15 cases) undergoing bone augmentation with titanium barriers combined with bone graft biomaterials for dental implant placement. Bone gain was assessed using pre- and postoperative low-dose cone beam computed tomography (CBCT) measurements in vertical and horizontal planes. Histological analyses evaluated the quality and vascularization of the regenerated bone. Results: Significant bone volume increases were observed, with a mean vertical gain of 7.60 mm (SD 0.23) and a horizontal gain of 5.44 mm (SD 0.39). Histological examination confirmed well-vascularized regenerated bone with minimal residual graft material, effective integration, and the formation of keratinized gingiva. Conclusions: Titanium occlusive barriers in GBR provide a reliable and minimally invasive method for substantial bone regeneration, showing advantages such as ease of handling and reduced invasiveness. Additional studies are recommended to validate these findings and evaluate long-term outcomes. |
| format | Article |
| id | doaj-art-6335d87f9039497d985331f521eb797b |
| institution | Kabale University |
| issn | 2313-7673 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomimetics |
| spelling | doaj-art-6335d87f9039497d985331f521eb797b2025-08-20T03:43:21ZengMDPI AGBiomimetics2313-76732025-03-0110316510.3390/biomimetics10030165Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone AugmentationLuis Leiva-Gea0Paulino Sánchez-Palomino1Alfonso Lendínez-Jurado2María Daniela Corte-Torres3Isabel Leiva-Gea4Antonio Leiva-Gea5Clínicas ClearDent, 23006 Jaén, SpainFacultad de Odontología, Universidad de Granada, 18011 Granada, SpainHospital Regional Universitario de Málaga, 29011 Málaga, SpainBiobanco del Principado de Asturias, FINBA-ISPA, 33011 Oviedo, SpainHospital Regional Universitario de Málaga, 29011 Málaga, SpainInstituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma BIONAND, 29010 Málaga, SpainBackground: Guided bone regeneration (GBR) is a widely used technique in oral and maxillofacial surgery to restore lost bone. The aim of this study is to evaluate the effectiveness of titanium occlusive barriers in GBR for increasing bone volume in both vertical and horizontal dimensions. Methods: A prospective analysis was conducted on 11 patients (15 cases) undergoing bone augmentation with titanium barriers combined with bone graft biomaterials for dental implant placement. Bone gain was assessed using pre- and postoperative low-dose cone beam computed tomography (CBCT) measurements in vertical and horizontal planes. Histological analyses evaluated the quality and vascularization of the regenerated bone. Results: Significant bone volume increases were observed, with a mean vertical gain of 7.60 mm (SD 0.23) and a horizontal gain of 5.44 mm (SD 0.39). Histological examination confirmed well-vascularized regenerated bone with minimal residual graft material, effective integration, and the formation of keratinized gingiva. Conclusions: Titanium occlusive barriers in GBR provide a reliable and minimally invasive method for substantial bone regeneration, showing advantages such as ease of handling and reduced invasiveness. Additional studies are recommended to validate these findings and evaluate long-term outcomes.https://www.mdpi.com/2313-7673/10/3/165guided bone regenerationtitanium barriersbone augmentationdental implants |
| spellingShingle | Luis Leiva-Gea Paulino Sánchez-Palomino Alfonso Lendínez-Jurado María Daniela Corte-Torres Isabel Leiva-Gea Antonio Leiva-Gea Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone Augmentation Biomimetics guided bone regeneration titanium barriers bone augmentation dental implants |
| title | Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone Augmentation |
| title_full | Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone Augmentation |
| title_fullStr | Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone Augmentation |
| title_full_unstemmed | Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone Augmentation |
| title_short | Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone Augmentation |
| title_sort | effectiveness of titanium occlusive barriers in guided bone regeneration a prospective analysis of vertical and horizontal bone augmentation |
| topic | guided bone regeneration titanium barriers bone augmentation dental implants |
| url | https://www.mdpi.com/2313-7673/10/3/165 |
| work_keys_str_mv | AT luisleivagea effectivenessoftitaniumocclusivebarriersinguidedboneregenerationaprospectiveanalysisofverticalandhorizontalboneaugmentation AT paulinosanchezpalomino effectivenessoftitaniumocclusivebarriersinguidedboneregenerationaprospectiveanalysisofverticalandhorizontalboneaugmentation AT alfonsolendinezjurado effectivenessoftitaniumocclusivebarriersinguidedboneregenerationaprospectiveanalysisofverticalandhorizontalboneaugmentation AT mariadanielacortetorres effectivenessoftitaniumocclusivebarriersinguidedboneregenerationaprospectiveanalysisofverticalandhorizontalboneaugmentation AT isabelleivagea effectivenessoftitaniumocclusivebarriersinguidedboneregenerationaprospectiveanalysisofverticalandhorizontalboneaugmentation AT antonioleivagea effectivenessoftitaniumocclusivebarriersinguidedboneregenerationaprospectiveanalysisofverticalandhorizontalboneaugmentation |