Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil Solution
Background. The research results of fat-soluble vitamin D3 (cholecalciferol) encapsulation with β-cyclodextrin have been presented in this work. The vitamin D3 inclusion complex with β-cyclodextrin was obtained under microwave radiation. The surface morphology of obtained clathrate inclusion complex...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Scientifica |
| Online Access: | http://dx.doi.org/10.1155/2020/6148939 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832566481531961344 |
|---|---|
| author | Ryszhan Bakirova Altynbek Nukhuly Ainara Iskineyeva Serik Fazylov Meiram Burkeyev Ayaulym Mustafayeva Yelena Minayeva Akmaral Sarsenbekova |
| author_facet | Ryszhan Bakirova Altynbek Nukhuly Ainara Iskineyeva Serik Fazylov Meiram Burkeyev Ayaulym Mustafayeva Yelena Minayeva Akmaral Sarsenbekova |
| author_sort | Ryszhan Bakirova |
| collection | DOAJ |
| description | Background. The research results of fat-soluble vitamin D3 (cholecalciferol) encapsulation with β-cyclodextrin have been presented in this work. The vitamin D3 inclusion complex with β-cyclodextrin was obtained under microwave radiation. The surface morphology of obtained clathrate inclusion complexes was described with the help of a scanning electron microscope. The thermographic measurement results on a differential scanning calorimeter have been presented. The activation energy of the β-cyclodextrin : vitamin D3 clathrate complex thermal oxidative destruction reaction was calculated. The clathrate thermal destruction kinetic parameters were determined. The inclusion complex spectral properties were characterized by IR-Fourier and 1H and 13C NMR spectroscopy. The existence of β-cyclodextrin inclusion complex with vitamin D3 in a 2 : 1 ratio was confirmed by the experimental results. The activation energy of thermal destruction of the inclusion complex of β-cyclodextrin with vitamin D3 was calculated using four different methods. |
| format | Article |
| id | doaj-art-63331cd2582b4113ad98643c8e8da574 |
| institution | Kabale University |
| issn | 2090-908X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Scientifica |
| spelling | doaj-art-63331cd2582b4113ad98643c8e8da5742025-02-03T01:04:00ZengWileyScientifica2090-908X2020-01-01202010.1155/2020/61489396148939Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil SolutionRyszhan Bakirova0Altynbek Nukhuly1Ainara Iskineyeva2Serik Fazylov3Meiram Burkeyev4Ayaulym Mustafayeva5Yelena Minayeva6Akmaral Sarsenbekova7Karaganda Medical University, Non-Commercial Joint-Stock Company, Karaganda, KazakhstanPavlodar State Pedagogical University, Pavlodar, KazakhstanSaken Seifullin Kazakh Agrotechnical University, Nur-Sultan, KazakhstanKaraganda State University, Karaganda, KazakhstanKaraganda State University, Karaganda, KazakhstanSaken Seifullin Kazakh Agrotechnical University, Nur-Sultan, KazakhstanKaraganda State University, Karaganda, KazakhstanKaraganda State University, Karaganda, KazakhstanBackground. The research results of fat-soluble vitamin D3 (cholecalciferol) encapsulation with β-cyclodextrin have been presented in this work. The vitamin D3 inclusion complex with β-cyclodextrin was obtained under microwave radiation. The surface morphology of obtained clathrate inclusion complexes was described with the help of a scanning electron microscope. The thermographic measurement results on a differential scanning calorimeter have been presented. The activation energy of the β-cyclodextrin : vitamin D3 clathrate complex thermal oxidative destruction reaction was calculated. The clathrate thermal destruction kinetic parameters were determined. The inclusion complex spectral properties were characterized by IR-Fourier and 1H and 13C NMR spectroscopy. The existence of β-cyclodextrin inclusion complex with vitamin D3 in a 2 : 1 ratio was confirmed by the experimental results. The activation energy of thermal destruction of the inclusion complex of β-cyclodextrin with vitamin D3 was calculated using four different methods.http://dx.doi.org/10.1155/2020/6148939 |
| spellingShingle | Ryszhan Bakirova Altynbek Nukhuly Ainara Iskineyeva Serik Fazylov Meiram Burkeyev Ayaulym Mustafayeva Yelena Minayeva Akmaral Sarsenbekova Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil Solution Scientifica |
| title | Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil Solution |
| title_full | Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil Solution |
| title_fullStr | Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil Solution |
| title_full_unstemmed | Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil Solution |
| title_short | Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil Solution |
| title_sort | obtaining and investigation of the β cyclodextrin inclusion complex with vitamin d3 oil solution |
| url | http://dx.doi.org/10.1155/2020/6148939 |
| work_keys_str_mv | AT ryszhanbakirova obtainingandinvestigationofthebcyclodextrininclusioncomplexwithvitamind3oilsolution AT altynbeknukhuly obtainingandinvestigationofthebcyclodextrininclusioncomplexwithvitamind3oilsolution AT ainaraiskineyeva obtainingandinvestigationofthebcyclodextrininclusioncomplexwithvitamind3oilsolution AT serikfazylov obtainingandinvestigationofthebcyclodextrininclusioncomplexwithvitamind3oilsolution AT meiramburkeyev obtainingandinvestigationofthebcyclodextrininclusioncomplexwithvitamind3oilsolution AT ayaulymmustafayeva obtainingandinvestigationofthebcyclodextrininclusioncomplexwithvitamind3oilsolution AT yelenaminayeva obtainingandinvestigationofthebcyclodextrininclusioncomplexwithvitamind3oilsolution AT akmaralsarsenbekova obtainingandinvestigationofthebcyclodextrininclusioncomplexwithvitamind3oilsolution |