The biological role and molecular mechanism of transfer RNA-derived small RNAs in tumor metastasis

The biological role and molecular mechanism of transfer RNA-derived small RNAs in tumor metastasis

Tumor metastasis is a significant contributor to increased cancer mortality. Transfer RNA-derived small RNAs (tsRNAs), a class of endogenous non-coding RNA molecules, play crucial functional roles in various physiological processes, including the regulation of transcription and reverse transcription...

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Bibliographic Details
Main Authors: Haotian Dong, Chengyuan Ye, Xiaohan Ye, Jianing Yan, Guoliang Ye, Yongfu Shao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
tsRNA
tumor metastasis
signaling pathway
epithelial-mesenchymal transition
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1560943/full
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