A Multicellular In Vitro Model of the Human Intestine with Immunocompetent Features Highlights Host‐Pathogen Interactions During Early Salmonella Typhimurium Infection

A Multicellular In Vitro Model of the Human Intestine with Immunocompetent Features Highlights Host‐Pathogen Interactions During Early Salmonella Typhimurium Infection

Abstract Studying the molecular basis of intestinal infections caused by enteric pathogens at the tissue level is challenging, because most human intestinal infection models have limitations, and results obtained from animals may not reflect the human situation. Infections with Salmonella enterica s...

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Bibliographic Details
Main Authors: Spyridon Damigos, Aylin Caliskan, Gisela Wajant, Sara Giddins, Adriana Moldovan, Sabine Kuhn, Evelyn Putz, Thomas Dandekar, Thomas Rudel, Alexander J. Westermann, Daniela Zdzieblo
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
host‐pathogen interaction
human in vitro infection models
immunocompetent models
intestinal tissue models
microfold cells
organoids
Online Access:https://doi.org/10.1002/advs.202411233
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