Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology

Spectral imaging methods are attracting increased interest from researchers and practitioners in basic science, pre-clinical and clinical arenas. A combination of better labeling reagents and better optics creates opportunities to detect and measure multiple parameters at the molecular and cellular...

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Main Authors: Richard Levenson, Joseph Beechem, George McNamara
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-2012-0062
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author Richard Levenson
Joseph Beechem
George McNamara
author_facet Richard Levenson
Joseph Beechem
George McNamara
author_sort Richard Levenson
collection DOAJ
description Spectral imaging methods are attracting increased interest from researchers and practitioners in basic science, pre-clinical and clinical arenas. A combination of better labeling reagents and better optics creates opportunities to detect and measure multiple parameters at the molecular and cellular level. These tools can provide valuable insights into the basic mechanisms of life, and yield diagnostic and prognostic information for clinical applications. There are many multispectral technologies available, each with its own advantages and limitations. This chapter will present an overview of the rationale for spectral imaging, and discuss the hardware, software and sample labeling strategies that can optimize its usefulness in clinical settings.
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spelling doaj-art-631f12941d1b40cd9719aa32fc9b05e92025-08-20T02:35:12ZengWileyAnalytical Cellular Pathology2210-71772210-71852012-01-01355-633936110.3233/ACP-2012-0062Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical PathologyRichard Levenson0Joseph Beechem1George McNamara2Pathology and Laboratory Medicine, University of California Davis, Sacramento, CA, USAGenetic Systems, Life Technologies, Foster City, CA, USAAnalytical Imaging Core, University of Miami School of Medicine, Miami, FL, USASpectral imaging methods are attracting increased interest from researchers and practitioners in basic science, pre-clinical and clinical arenas. A combination of better labeling reagents and better optics creates opportunities to detect and measure multiple parameters at the molecular and cellular level. These tools can provide valuable insights into the basic mechanisms of life, and yield diagnostic and prognostic information for clinical applications. There are many multispectral technologies available, each with its own advantages and limitations. This chapter will present an overview of the rationale for spectral imaging, and discuss the hardware, software and sample labeling strategies that can optimize its usefulness in clinical settings.http://dx.doi.org/10.3233/ACP-2012-0062
spellingShingle Richard Levenson
Joseph Beechem
George McNamara
Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology
Analytical Cellular Pathology
title Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology
title_full Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology
title_fullStr Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology
title_full_unstemmed Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology
title_short Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology
title_sort modern trends in imaging x spectral imaging in preclinical research and clinical pathology
url http://dx.doi.org/10.3233/ACP-2012-0062
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