Fulminant Hepatic Failure in the Course of an Outpatient Anesthetic Procedure: Sevoflurane among Other High-Risk Factors
A 20-year-old man underwent an outpatient general anesthetic procedure with sevoflurane for the correction of a bilateral gynecomastia. The patient had been first exposed to sevoflurane two years before, without any complication. He presented an overweight with a body mass index (BMI) of 31.4 kg/m2...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Anesthesiology |
| Online Access: | http://dx.doi.org/10.1155/2020/5124098 |
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| author | Céline Cheron Perrine Hoet Nathalie Renard Geoffroy Vanderweerden Cristina Miscu Mina Komuta Pierre-François Laterre Philippe Hantson |
| author_facet | Céline Cheron Perrine Hoet Nathalie Renard Geoffroy Vanderweerden Cristina Miscu Mina Komuta Pierre-François Laterre Philippe Hantson |
| author_sort | Céline Cheron |
| collection | DOAJ |
| description | A 20-year-old man underwent an outpatient general anesthetic procedure with sevoflurane for the correction of a bilateral gynecomastia. The patient had been first exposed to sevoflurane two years before, without any complication. He presented an overweight with a body mass index (BMI) of 31.4 kg/m2 and had an episode of “binge” drinking a few days before anesthesia. He became icteric from postoperative day 9, and after the worsening of liver function tests, the liver biopsy revealed centrilobular necrosis. The patient became encephalopathic and required urgent liver transplantation on postoperative day 30. The possibility of a sevoflurane-related fulminant hepatic failure is discussed. |
| format | Article |
| id | doaj-art-6305eefc7dfa45178a128c33932c320a |
| institution | Kabale University |
| issn | 2090-6382 2090-6390 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Anesthesiology |
| spelling | doaj-art-6305eefc7dfa45178a128c33932c320a2025-02-03T06:43:44ZengWileyCase Reports in Anesthesiology2090-63822090-63902020-01-01202010.1155/2020/51240985124098Fulminant Hepatic Failure in the Course of an Outpatient Anesthetic Procedure: Sevoflurane among Other High-Risk FactorsCéline Cheron0Perrine Hoet1Nathalie Renard2Geoffroy Vanderweerden3Cristina Miscu4Mina Komuta5Pierre-François Laterre6Philippe Hantson7Department of Intensive Care, Université Catholique de Louvain, Cliniques St-Luc, 1200 Brussels, BelgiumLouvain Centre for Toxicology and Applied Pharmacology, Université Catholique de Louvain, 1200 Brussels, BelgiumDepartment of Pathology, Centre Hospitalier de Wallonie Picarde, Tournai, BelgiumDepartment of Anesthesiology, Centre Hospitalier de Wallonie Picarde, Tournai, BelgiumDepartment of Gastroenterology, Centre Hospitalier de Wallonie Picarde, Tournai, BelgiumDepartment of Pathology, Université Catholique de Louvain, Cliniques St-Luc, 1200 Brussels, BelgiumDepartment of Intensive Care, Université Catholique de Louvain, Cliniques St-Luc, 1200 Brussels, BelgiumDepartment of Intensive Care, Université Catholique de Louvain, Cliniques St-Luc, 1200 Brussels, BelgiumA 20-year-old man underwent an outpatient general anesthetic procedure with sevoflurane for the correction of a bilateral gynecomastia. The patient had been first exposed to sevoflurane two years before, without any complication. He presented an overweight with a body mass index (BMI) of 31.4 kg/m2 and had an episode of “binge” drinking a few days before anesthesia. He became icteric from postoperative day 9, and after the worsening of liver function tests, the liver biopsy revealed centrilobular necrosis. The patient became encephalopathic and required urgent liver transplantation on postoperative day 30. The possibility of a sevoflurane-related fulminant hepatic failure is discussed.http://dx.doi.org/10.1155/2020/5124098 |
| spellingShingle | Céline Cheron Perrine Hoet Nathalie Renard Geoffroy Vanderweerden Cristina Miscu Mina Komuta Pierre-François Laterre Philippe Hantson Fulminant Hepatic Failure in the Course of an Outpatient Anesthetic Procedure: Sevoflurane among Other High-Risk Factors Case Reports in Anesthesiology |
| title | Fulminant Hepatic Failure in the Course of an Outpatient Anesthetic Procedure: Sevoflurane among Other High-Risk Factors |
| title_full | Fulminant Hepatic Failure in the Course of an Outpatient Anesthetic Procedure: Sevoflurane among Other High-Risk Factors |
| title_fullStr | Fulminant Hepatic Failure in the Course of an Outpatient Anesthetic Procedure: Sevoflurane among Other High-Risk Factors |
| title_full_unstemmed | Fulminant Hepatic Failure in the Course of an Outpatient Anesthetic Procedure: Sevoflurane among Other High-Risk Factors |
| title_short | Fulminant Hepatic Failure in the Course of an Outpatient Anesthetic Procedure: Sevoflurane among Other High-Risk Factors |
| title_sort | fulminant hepatic failure in the course of an outpatient anesthetic procedure sevoflurane among other high risk factors |
| url | http://dx.doi.org/10.1155/2020/5124098 |
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