A case report of squamous cell carcinoma in ichthyosis hystrix Curth-Macklin
The Curth-Macklin type of ichthyosis hystrix is an extremely rare genodermatosis presenting as generalized or nevoid forms. Clinical expression varies in the time of onset and morphology, even within families, from painful palmoplantar keratoderma to a severe, generalized involvement with hyperkerat...
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| Language: | English |
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Galenos Publishing House
2024-12-01
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| Series: | Turkderm Turkish Archives of Dermatology and Venereology |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=turkderm&un=TURKDERM-30837 |
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| author | Vishalakshi Pandit Rakesh Yelhanka |
| author_facet | Vishalakshi Pandit Rakesh Yelhanka |
| author_sort | Vishalakshi Pandit |
| collection | DOAJ |
| description | The Curth-Macklin type of ichthyosis hystrix is an extremely rare genodermatosis presenting as generalized or nevoid forms. Clinical expression varies in the time of onset and morphology, even within families, from painful palmoplantar keratoderma to a severe, generalized involvement with hyperkeratotic and papillomatous coalescent papules distributed extensively and bilaterally in whorled arrays of thickened, darkened, hystrixlike velvety lesions anywhere on the skin surface. There are few case reports of patients with ichthyosis hystrix who developed malignancies. We report a sporadic case of a 73-year-old man who presented with an unusual manifestation of ichthyosis hystrix and developed squamous cell carcinoma. Ichthyosis hystrix Curth-Macklin is a rare congenital ichthyosis that has developed multiple keratoses and malignancies over a long time. Therefore, early diagnosis, treatment, and regular follow-up are required in these patients. |
| format | Article |
| id | doaj-art-6301e47924bf4953858381cb4694276c |
| institution | Kabale University |
| issn | 2651-5164 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Turkderm Turkish Archives of Dermatology and Venereology |
| spelling | doaj-art-6301e47924bf4953858381cb4694276c2025-01-07T11:22:03ZengGalenos Publishing HouseTurkderm Turkish Archives of Dermatology and Venereology2651-51642024-12-0158412112410.4274/turkderm.galenos.2024.30837TURKDERM-30837A case report of squamous cell carcinoma in ichthyosis hystrix Curth-MacklinVishalakshi Pandit0Rakesh Yelhanka1Koppal Institute of Medical Sciences, Department of Dermatology, Koppal, Karnataka, IndiaKoppal Institute of Medical Sciences, Venereology and Leprosy, Koppal, Karnataka, IndiaThe Curth-Macklin type of ichthyosis hystrix is an extremely rare genodermatosis presenting as generalized or nevoid forms. Clinical expression varies in the time of onset and morphology, even within families, from painful palmoplantar keratoderma to a severe, generalized involvement with hyperkeratotic and papillomatous coalescent papules distributed extensively and bilaterally in whorled arrays of thickened, darkened, hystrixlike velvety lesions anywhere on the skin surface. There are few case reports of patients with ichthyosis hystrix who developed malignancies. We report a sporadic case of a 73-year-old man who presented with an unusual manifestation of ichthyosis hystrix and developed squamous cell carcinoma. Ichthyosis hystrix Curth-Macklin is a rare congenital ichthyosis that has developed multiple keratoses and malignancies over a long time. Therefore, early diagnosis, treatment, and regular follow-up are required in these patients.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=turkderm&un=TURKDERM-30837ichthyosis hystrixhyperkeratosismalignancy |
| spellingShingle | Vishalakshi Pandit Rakesh Yelhanka A case report of squamous cell carcinoma in ichthyosis hystrix Curth-Macklin Turkderm Turkish Archives of Dermatology and Venereology ichthyosis hystrix hyperkeratosis malignancy |
| title | A case report of squamous cell carcinoma in ichthyosis hystrix Curth-Macklin |
| title_full | A case report of squamous cell carcinoma in ichthyosis hystrix Curth-Macklin |
| title_fullStr | A case report of squamous cell carcinoma in ichthyosis hystrix Curth-Macklin |
| title_full_unstemmed | A case report of squamous cell carcinoma in ichthyosis hystrix Curth-Macklin |
| title_short | A case report of squamous cell carcinoma in ichthyosis hystrix Curth-Macklin |
| title_sort | case report of squamous cell carcinoma in ichthyosis hystrix curth macklin |
| topic | ichthyosis hystrix hyperkeratosis malignancy |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=turkderm&un=TURKDERM-30837 |
| work_keys_str_mv | AT vishalakshipandit acasereportofsquamouscellcarcinomainichthyosishystrixcurthmacklin AT rakeshyelhanka acasereportofsquamouscellcarcinomainichthyosishystrixcurthmacklin AT vishalakshipandit casereportofsquamouscellcarcinomainichthyosishystrixcurthmacklin AT rakeshyelhanka casereportofsquamouscellcarcinomainichthyosishystrixcurthmacklin |