Adults in Ghana generate higher and more durable neutralising antibody titres following primary course COVID-19 vaccination than matched UK adults: The HERITAGE Study

Adults in Ghana generate higher and more durable neutralising antibody titres following primary course COVID-19 vaccination than matched UK adults: The HERITAGE Study

Abstract Background Little data exist on the COVID-19 vaccine response in African countries who despite having high disease burden, have low COVID-19 mortality rates. We investigated the longitudinal immune response in a West-African urban population upon COVID-19 vaccination, two years after the st...

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Main Authors: Eliza Mari Kwesi-Maliepaard, Yakubu Alhassan, Emmanuel K. Quaye, Vera M. Kotey, Aisha M. Mohammed, Seth Agyemang, Adelaide K. Sromani, Stephanie Darko, Erica Buadii, Randy Tackie, Harry Akligoh, Barikisu Ibrahim, David Hutchful, Lily Paemka, Emmanuella Amoako, Joyce M. Ngoi, Aida Manu, the HERITAGE study team, David Greenwood, Edward J. Carr, Mary Y. Wu, David L. V. Bauer, Emma C. Wall, the Crick Legacy Consortium, Dzifa Dey, Abdul Razak Quao, Akosua Ayisi, Kwame Amponsa-Achiano, Franklin Asiedu Bekoe, Gordon Awandare, Peter K. Quashie, Yaw Bediako
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Medicine
Subjects:
SARS-CoV-2
COVID-19 vaccine
Africa
Vaccine response
Geographical variation
Online Access:https://doi.org/10.1186/s12916-025-04157-0
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