Relationship between vascular calcification, osteoporosis and systemic inflammation
A lot of patients with coronary heart disease often suffer from vascular calcification. In many cases it is accompanied by harmful cardiovascular events. The modern ideas of the relationship between osteoporosis, vascular calcification and inflammation, the general mechanisms of development of vascu...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Siberian Branch Publishing House
2024-01-01
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| Series: | Сибирский научный медицинский журнал |
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| Online Access: | https://sibmed.elpub.ru/jour/article/view/1302 |
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| author | K. A. Nichiporuk S. Yu. Tsarenok V. V. Gorbunov N. A. Ilyamakova T. A. Aksenova |
| author_facet | K. A. Nichiporuk S. Yu. Tsarenok V. V. Gorbunov N. A. Ilyamakova T. A. Aksenova |
| author_sort | K. A. Nichiporuk |
| collection | DOAJ |
| description | A lot of patients with coronary heart disease often suffer from vascular calcification. In many cases it is accompanied by harmful cardiovascular events. The modern ideas of the relationship between osteoporosis, vascular calcification and inflammation, the general mechanisms of development of vascular calcification and low bone mineral density are discussed. Despite a growing number of studies concerning the combined pathology of the cardiovascular and skeletal systems, a causal relationship between vascular calcification and a decrease in bone mass has not yet been established. Moreover, there is insufficient data on the effect of inflammation on ectopic calcification. Based on the analysis of available clinical and experimental studies, this review describes the main pathogenetic mechanisms of vascular calcification in coronary atherosclerosis. The influence of calcium and vitamin D medicines on the development of vascular calcification is discussed in this article. The author’s attention is focused on early and long-term consequences of percutaneous coronary intervention and coronary bypass surgery in patients with vascular calcification. |
| format | Article |
| id | doaj-art-62f25517110d490c83e72a9ed0600a5a |
| institution | Kabale University |
| issn | 2410-2512 2410-2520 |
| language | Russian |
| publishDate | 2024-01-01 |
| publisher | Russian Academy of Sciences, Siberian Branch Publishing House |
| record_format | Article |
| series | Сибирский научный медицинский журнал |
| spelling | doaj-art-62f25517110d490c83e72a9ed0600a5a2025-08-20T03:50:44ZrusRussian Academy of Sciences, Siberian Branch Publishing HouseСибирский научный медицинский журнал2410-25122410-25202024-01-01436142310.18699/SSMJ20230602554Relationship between vascular calcification, osteoporosis and systemic inflammationK. A. Nichiporuk0S. Yu. Tsarenok1V. V. Gorbunov2N. A. Ilyamakova3T. A. Aksenova4Chita State Medical Academy of Minzdrav of RussiaChita State Medical Academy of Minzdrav of RussiaChita State Medical Academy of Minzdrav of RussiaClinical Hospital “RR-Medicine” of ChitaChita State Medical Academy of Minzdrav of RussiaA lot of patients with coronary heart disease often suffer from vascular calcification. In many cases it is accompanied by harmful cardiovascular events. The modern ideas of the relationship between osteoporosis, vascular calcification and inflammation, the general mechanisms of development of vascular calcification and low bone mineral density are discussed. Despite a growing number of studies concerning the combined pathology of the cardiovascular and skeletal systems, a causal relationship between vascular calcification and a decrease in bone mass has not yet been established. Moreover, there is insufficient data on the effect of inflammation on ectopic calcification. Based on the analysis of available clinical and experimental studies, this review describes the main pathogenetic mechanisms of vascular calcification in coronary atherosclerosis. The influence of calcium and vitamin D medicines on the development of vascular calcification is discussed in this article. The author’s attention is focused on early and long-term consequences of percutaneous coronary intervention and coronary bypass surgery in patients with vascular calcification.https://sibmed.elpub.ru/jour/article/view/1302coronary atherosclerosisosteoporosisbone mineral densityectopic calcificationvascular calcificationinflammation |
| spellingShingle | K. A. Nichiporuk S. Yu. Tsarenok V. V. Gorbunov N. A. Ilyamakova T. A. Aksenova Relationship between vascular calcification, osteoporosis and systemic inflammation Сибирский научный медицинский журнал coronary atherosclerosis osteoporosis bone mineral density ectopic calcification vascular calcification inflammation |
| title | Relationship between vascular calcification, osteoporosis and systemic inflammation |
| title_full | Relationship between vascular calcification, osteoporosis and systemic inflammation |
| title_fullStr | Relationship between vascular calcification, osteoporosis and systemic inflammation |
| title_full_unstemmed | Relationship between vascular calcification, osteoporosis and systemic inflammation |
| title_short | Relationship between vascular calcification, osteoporosis and systemic inflammation |
| title_sort | relationship between vascular calcification osteoporosis and systemic inflammation |
| topic | coronary atherosclerosis osteoporosis bone mineral density ectopic calcification vascular calcification inflammation |
| url | https://sibmed.elpub.ru/jour/article/view/1302 |
| work_keys_str_mv | AT kanichiporuk relationshipbetweenvascularcalcificationosteoporosisandsystemicinflammation AT syutsarenok relationshipbetweenvascularcalcificationosteoporosisandsystemicinflammation AT vvgorbunov relationshipbetweenvascularcalcificationosteoporosisandsystemicinflammation AT nailyamakova relationshipbetweenvascularcalcificationosteoporosisandsystemicinflammation AT taaksenova relationshipbetweenvascularcalcificationosteoporosisandsystemicinflammation |